ObjectiveTo explore the pathogenesis of cervical spondylosis combined with cervicogenic vertigo, and to investigate the clinical results of anterior discectomy and fusion in treating the disease. MethodsA retrospective study was performed on 83 patients with cervical spondylosis myelopathy (n=60, 72%) or radiculopathy (n=23, 37.3%) accompanied by sympathetic symptoms such as dizziness between March 2008 and November 2012. The disease involved single segment in 29 cases, double segment in 50 cases, and triple in 4 cases. All the segments involved were treated with anterior discectomy and fusion. Vertigo alleviation was observed before surgery, 3 days after surgery, and during the final follow-up. Neurological status was evaluated by Japanese Orthopedic Association (JOA) score system and sympathetic symptoms were evaluated with vertigo symptom and function scoring system. ResultsThe average follow-up was 21 months (ranging from 12 to 30 months). Significant difference was observed between sympathetic symptom scores and JOA scores before surgery and 3 days after surgery or at the final follow-up (P<0.05), but no significant difference was found between the scores 3 days after surgery and during the final follow-up (P>0.05). ConclusionThe surgical effect for cervicogenic vertigo is often accompanied by the relief of spinal cord and nerve roots symptoms. Surgery is effective for cervical spondylosis combined with cervicogenic vertigo.
ObjectiveTo evaluate the effects and safety of ginkgo leaf extract and dipyridamole combined with betahistine injection for the treatment of vertebrobasilar ischemia with vertigo. MethodsThe Cochrane Library, Medline, Embase, Web of Science, China National Knowledge Infrastructure, VIP Database, Wanfang Database and China Biology Medicine Databases were searched from their establishment to September 2015. We used the method recommended by the Cochrane collaboration to perform a meta-analysis on randomized controlled trails. ResultsSix studies were included. The results of meta-analysis demonstrated that ginkgo leaf extract and dipyridamole combined with betahistine injection for the treatment of vertebrobasilar ischemia with vertigo was superior to either ginkgo leaf extract and dipyridamole or betahistine injection in total effective rate[RR=1.21, 95%CI (1.08, 1.35), P=0.000 7; RR=1.17, 95%CI (1.05, 1.31), P=0.006]. ConclusionGinkgo leaf extract and dipyridamole combined with betahistine injection is effective for the treatment of vertebrobasilar ischemia with vertigo. However, due to the limited quantity and quality of the included studies, the results need to be further confirmed.
Objectives To systematically review the efficacy and safety of bonesetting combined acupuncture in the treatment of cervical vertigo. Methods PubMed, CNKI, VIP, CBM and WanFang Data databases were searched to collect randomized controlled trials (RCTs) on bonesetting combined acupuncture in the treatment of cervical vertigo from inception to February 15th, 2017. Two reviewers independently screened literature, extracted data and assessed the risk of bias of the included studies. Meta-analysis was performed by RevMan 5.3 software. Results Eighteenth RCTs involving 1 915 patients were included. The results of meta-analysis showed that, compared with acupuncture or bonesetting alone group, the effective rate in bonesetting combining acupuncture group was higher (RRacupuncture=1.17, 95%CI 1.12 to 1.23, P<0.000 01; RRbonesetting=1.16, 95%CI 1.10 to 1.23, P<0.000 01). Improvement of the cervical vertigo symptom and function in the combined group was better than that in the acupuncture group or bonesetting group (MDacupuncture=3.42, 95%CI 2.29 to 4.56, P<0.000 01; MDbonesetting=6.45, 95%CI 5.56 to 7.33, P<0.000 01). Average flow velocity of cervical vertigo basilar artery (BA) in the combined group was superior to the bonesetting group (MD=7.54, 95%CIP=0.02). 1.08 to 13.99, Conclusions Bonesetting combining acupuncture treatment of cervical vertigo in terms of effectiveness and function improvement are better than those of acupuncture alone or pure bonesetting. Due to the limited quality and quantity of the included studies, more high-quality studies are required to verify above conclusions.
With the aging of the population, the incidence of benign paroxysmal positional vertigo (BPPV) and osteoporosis have been increasing year by year, and the incidence of BPPV in vertigo related diseases has also been ranked first. There are similarities in structure, formation and metabolic mechanism between bone and otolith, but there is no consistent conclusion on the relationship between BPPV and osteoporosis. This article summarizes the current situation of the research on the correlation between BPPV and osteoporosis, the common risk factors and the related co-occurring mechanisms, aiming to provide more ideas for the prevention and treatment of BPPV patients, and improve the prevention and treatment ability of the co-diseases in the elderly.
Vestibular dysfunction is a clinical syndrome characterized by symptoms such as dizziness or vertigo, abnormal control of eye movements, balance disorders, and autonomic nervous system symptoms. Immune-related vestibular dysfunction is caused by vestibular abnormalities triggered by autoimmune reactions or dysfunctions in the immune system. Some autoimmune diseases can present with vestibular dysfunction as the initial symptom or a typical manifestation. There is still a lack of understanding regarding the immune pathogenic factors of vestibular abnormalities both domestically and internationally. This paper provides a detailed summary of the types, onset, pathological mechanisms, symptoms, signs, and auxiliary examinations of immune-related vestibular dysfunction, aiming to offer new insights for the identification of such diseases.