Esophageal carcinoma is a malignant tumor with high morbidity and mortality worldwide, and surgery is the main treatment currently. With the development of patient-centered care, the effect of surgery should not be limited to the improvement of the incidence of postoperative complications, mortality and other indicators. It is also important to provide experience related to disease and surgery from the perspective of patients. Therefore, more and more attention is paid to patient-reported outcomes by scholars. This paper will provide an overview of the international widely used, reliable and effective scales and researches about patient-reported outcomes in esophageal carcinoma.
Objective To analyze the current research status, hotspots and development trends in the field of evidence-based health policy briefs at home and abroad. Methods Computer searches of Web of Science Core Collection and CNKI databases for studies related to evidence-based health policy briefs were conducted, and the timeframe of the searches was from the establishment of the databases to August 6, 2024. Charticular, VOSviewer and CiteSpace software were used to visualize and analyze the countries, institutions, journals, authors and keywords of the included literature. Results A total of 145 relevant studies were included, of which 141 were in English and 4 were in Chinese. The number of articles in English showed an overall increasing trend; the country with the largest number of articles was the United States; the organization with the largest number of articles was the World Health Organization; the journal with the largest number of articles was Frontiers in Public Health; and the hot keywords in recent years focused on the food and nutritional safety system, cardiovascular disease, obesity, impact, and public health policy. The research related to "healthcare" and "knowledge translation" is expected to become a frontier hotspot. The number of Chinese studies was relatively small, and the research content involved policy briefs and policy brief methodology in the field of public health. Conclusion Future research may focus on policy briefs on health care, food and nutrition, cardiovascular disease, obesity and other health issues, their impact and the use of policy briefs in the formulation of public health policies. Currently, there is a significant difference between domestic and foreign research in the field of evidence-based health policy briefs, foreign research has tended to mature, while the domestic is still in the embryonic stage, there is an urgent need to enrich the methodological system, enrich the content of the study, and in the future, we can learn from the advanced experience of foreign countries and integrate multidisciplinary research methods, in order to promote the improvement and sustainable development of the field of evidence-based health policy briefs in China.
ObjectiveTo analyze the research status and hot spots of health technology assessment (HTA). MethodsDatabases including China National Knowledge Infrastructure (CNKI) and PubMed were searched to collect published studies on HTA. The software of BICOMS-2 and VOSviewer 1.6.10 was used to draw the network diagram and to conduct cluster analysis of keywords. ResultsA total of 1170 studies in Chinese and 8584 studies in English were included. The number of HTA-related publications increased annually, among which countries with the most publications were the United States, the United Kingdom, and Canada. Fudan University had the largest number of studies published in Chinese and York University had the largest number of studies published in English. The research topics mainly focused on hospital HTA, HTA decision transformation research, pharmacoeconomic evaluation, etc. The most frequent diseases were cancer and depression. Emerging keywords were real-word evidence, randomized controlled trials, cost-benefit analysis, etc. ConclusionHTA-related studies increase annually. Many HTA-related studies are performed in developed countries, such as the United States and the United Kingdom. The relevant research topics involve hospital HTA, HTA decision-making transformation research, and pharmacoeconomic evaluation. Current research focus is on the evaluation of health economics in the field of cancer based on the evidence of real-world research and randomized controlled trials.
Objectives To analyze the status quo of projects on pension services funded by the National Natural Science Foundation of China (NSFC), with the aim of enlarging the perspective and horizon of related studies, and improving both the quantity and quality of such projects in NSFC. Methods NSFC website was systematically searched to collect information of pension service projects funded by NSFC from 2008 to 2017. SPSS 19.0 software was subsequently applied to analyze the characteristics of the projects in terms of study type, regional distribution, profession and institution, and fund scale, etc. Results A total of 39 projects on pension service were included, among which 12 were focused on related strategies (30.8%), 11 on related models (28.2%), and 6 on the effects of different interventions (15.4%). The 39 projects were unbalanced in terms of geographical distribution, institutions and research types. Conclusions NSFC should facilitate the research of pension service by expanding the related fund scale, increasing the fund support, strengthening the exchange of domestically different regions, and enhancing international cooperation.
ObjectiveTo explore the trend and hotspots of research in the field of peripherally inserted central catheter (PICC), so as to provide a reference for clinical nursing and nursing research in the field of vascular access in China.MethodsAll PICC-related articles from 1806 to November 22nd, 2018 were searched in the Foreign Medical Retrieval System. The publication amount, year of publication, language, country, journals and impact factor, high-yield authors and high-frequent medical subject headings (MeSH) of the PICC-related articles were analyzed by using frequency, cumulative frequency, and constituent ratio.ResultsA total of 1 550 articles were included. They were published in 586 journals, of which 393 were included in Science Citation Index. English was the dominant publication language, and the top high-yield country was the United States. The top 16 high-yield authors published 199 articles, the top 3 of whom all had published co-operative papers, ranging from 1 article to 19 articles. The top 3 high-frequent MeSHs were “Catheters, Indwelling” “Catheterization, Central Venous” “Central Venous Catheter”.ConclusionsPICC has become a hotspot in clinical research, and the publication amount of relative literature has increased rapidly since 2000. Chinese scholars should improve their English and carry out multi-center cooperative research to improve the quality of PICC-related literature.
In recent years, transcatheter aortic valve replacement (TAVR) has developed rapidly in China, and the number and quality of operations have increased significantly. TAVR has become an important treatment strategy for patients with severe aortic stenosis and regurgitation following surgical aortic valve replacement. Prosthesis-patient mismatch (PPM) is one of the main complications after TAVR, but the incidence of TAVR-related PPM is significantly lower than surgical aortic valve replacement. Most studies believe that PPM has no significant effect on the clinical prognosis of most patients after TAVR, and only increases postoperative mortality in a specific population. This article will review the incidence, influencing factors, impact on clinical prognosis and related coping strategies of PPM after TAVR.
ObjectiveTo summarize the clinical application and research status of bioactive glass (BAG) in bone repair.MethodsThe recently published literature concerning BAG in bone repair at home and abroad was reviewed and summarized.ResultsBAG has been widely used in clinical bone repair with a favorable effectiveness. In the experimental aspect, to meet different clinical application needs, BAG has been prepared in different forms, such as particles, prosthetic coating, drug and biological factor delivery system, bone cement, and scaffold. And the significant progress has been made.ConclusionBAG has been well studied in the field of bone repair due to its excellent bone repair performance, and it is expected to become a new generation of bone repair material.
Objective To summarize the role of N-myc downstream regulated gene 1 (NDRG1) and the advancement of it in tumor research. Methods Publications on line at home and abroad involving the roles of NDRG1 and the correlation between it and tumor were collected and reviewed. Results NDRG-1, has a number of important functions such as in organism responses in hypoxia, histological differentiation, and so on, especially plays a significant role in generation, metastasis, and invasion of cancer. Conclusion NDRG1 may be a candidate of metastasis relevant gene for cancer and may serve as a useful prognostic marker of carcinoma.
Technology in traditional Chinese medicine (TCM), which has a long history, provides excellent traditional culture and valuable spiritual wealth in China. TCM standardization technology will provide an important basis for guiding and evaluating the professional level and service quality of technicians in TCM. And it is also conducive to the sustainable development of TCM technology. However, at present, there is no relevant research on the development process of technical specifications for TCM. So, the urgent need is how to develop standardized technical specifications, and apply them to patients in practice. Therefore, this study first convened relevant experts, including TCM clinical experts, epidemiologists, methodology experts, etc., to form the core expert group, implementation group and quality assurance task group. According to the personnel functions, they are divided into technical specification steering committee, consensus expert group, secretariat group, external review group, evidence evaluation group, etc. Then, the initial entries are collected by systematically searching the current TCM technical guidelines, consensus and specifications and referring to the existing technical specifications. Finally, expert opinions were collected based on the Delphi survey, and the final reporting checklist of technical specifications for TCM was formed after consensus discussion. The study can provide evidence-based methodological guidance for the development of TCM technical specifications, and promote the standardization and internationalization of TCM technical specifications.