ObjectiveTo evaluate the effect of soft silicone dressing in radiation dermatitis after radiotherapy for head and neck tumors.MethodsThe data of Cochrane Library, Web of Science, JBI Library, CINAHL, Embase, Medline, China National Knowledge Infrastructure, Wanfang Database and Chinese Biomedical Literature Database were searched by computer, and the literature of soft silicone dressing in the treatment of radiation dermatitis were collected. The intervention group was treated with soft silicone dressing and the control group was treated with burn ointment and other methods. The retrieval time was from their inception to March 2019. After screening, quality evaluation and data extraction by two independent evaluators, meta-analysis was carried out by RevMan 5.3 software.ResultsA total of 7 articles were included, including 2 in English and 5 in Chinese, with a total of 487 patients. The results of meta-analysis showed that soft silicone dressing could shorten the wound healing time of radiation dermatitis [mean difference=−4.05 days, 95% confidence interval (CI) (−6.69, −1.42) days, P=0.003], reduce the severity of radiation dermatitis symptoms rated by the Radiation Therapy Oncology Group grade [odds ratio =7.99, 95% CI (2.69, 23.75), P=0.000 2], and reduce the score of Radiation-Induced Skin Reaction Assessment Scale (RISRAS) [standardized mean difference=−1.32, 95%CI (−2.64, −0.00), P=0.05]. To some extent, the curative effect was better than that of other methods. Wound healing time and RISRAS score combined with heterogeneity, after sensitivity analysis, the results were stable. ConclusionSoft silicone dressing can improve the concomitant symptoms of radiation dermatitis after radiotherapy of head and neck tumor, and may relieve the pain of radiation dermatitis to a certain extent, and promote the healing speed of dermatitis wound.
目的:探讨慢性湿疹和皮炎患者接触性致敏原及其特点。方法:应用斑贴试验分析178例慢性湿疹和皮炎患者接触性致敏原。结果:列前的致敏原分别是硫酸镍、甲醛、香料、对苯二胺、重铬酸钾、松香、橡胶、白降汞、乙二胺;引起手部湿疹和皮炎患者的致敏原主要是香料和重铬酸钾、躯干和四肢湿疹和皮炎患者的致敏原主要为硫酸镍和松香、头面部湿疹和皮炎患者的主要致敏原为甲醛和香料,脐周皮炎和系统性接触性皮炎患者的致敏原主要为硫酸镍。结论:斑贴试验有助于明确慢性湿疹和皮炎患者的接触性致敏原及其性质。
目的:探讨慢性湿疹和皮炎患者接触性致敏原及其特点。方法:应用斑贴试验分析178例慢性湿疹和皮炎患者接触性致敏原。结果:列前的致敏原分别是硫酸镍、甲醛、香料、对苯二胺、重铬酸钾、松香、橡胶、白降汞、乙二胺;引起手部湿疹和皮炎患者的致敏原主要是香料和重铬酸钾;躯干和四肢湿疹和皮炎患者的致敏原主要为硫酸镍和松香;头面部湿疹和皮炎患者的主要致敏原为甲醛和香料;脐周皮炎和系统性接触性皮炎患者的致敏原主要为硫酸镍。结论:斑贴试验有助于明确慢性湿疹和皮炎患者的接触性致敏原及其性质。
ObjectiveTo investigate the efficacy and nursing strategy of Comfeel transparent paste in treating peripheral inserted central catheter (PICC)-associated allergic dermatitis. MethodsSixty patients with PICC puncture-associated local allergic dermatitis treated between June 2011 and March 2013 were randomly divided into experimental group and control group with 30 patients in each group. The experimental group was treated with dexamethasone sodium phosphate and Comfeel transparent paste, while the control group was treated with dexamethasone sodium phosphate and 3M transparent dressing. The curative effect was compared between the two methods. ResultsTwelve patients were cured with a curing rate of 40.0% in the control group and 22 patients were cured, and the curing rate was 73.3% in the experimental group. The difference between them was significant (P<0.05). ConclusionTreatment with dexamethasone sodium phosphate and Comfeel transparent paste for PICC-associated allergic dermatitis is quite effective, and the patients felt comfortable with low pains. In addition, it reduces the extubation rate of PICC and improves the care quality.