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The Clinical Efficacy of Specially-made “Yinchen Chaiping Tang” Decoction in Treating Chronic Hepatitis B

目的　观察茵陈柴平汤治疗重度慢性乙型肝炎的疗效及不良反应。 方法　2009年3月－2010年3月，选择采用茵陈柴平汤联合常规保肝药物治疗50例重度慢性乙型肝炎患者（治疗组），并与50例仅用常规保肝药物治疗的重度慢性乙型肝炎患者（对照组）进行比较，观察治疗2、4周时的临床症状、肝功能及凝血酶原活动度等指标的变化。 结果　治疗2、4周时，治疗组在肝功能及凝血酶原活动度等指标均有显著改善，无严重不良反应；4周时，治疗组的症状缓解率（84%）明显高于对照组（66%）；其总有效率（96%）亦高于对照组（80%）。 结论　茵陈柴平汤治疗重度慢性乙型肝炎具有较好的临床疗效，且无严重不良反应。

Effectiveness of telephone and WeChat follow-up in patients discharged from hospital with retained chest drains after stage Ⅲ tuberculous empyema surgery

ObjectiveTo investigate the efficacy of combined telephone and WeChat follow-up for patients discharged with an indwelling closed thoracic drainage tube after surgery for stage Ⅲ tuberculous empyema. MethodsPatients with stage Ⅲ tuberculous empyema who were discharged with an indwelling drainage tube from the Department of Thoracic Surgery, Public Health Clinical Center of Chengdu, between November 2021 and November 2022 were enrolled in this study. They were divided into an observation group (combined telephone and WeChat follow-up) and a control group (telephone-only follow-up). The quality of life (QoL), treatment adherence, and recovery outcomes were compared between the two groups. Results A total of 81 patients were included. The observation group consisted of 49 patients (31 males, 18 females) with a mean age of (38.63±15.86) years. The control group consisted of 32 patients (27 males, 5 females) with a mean age of (36.91±17.33) years. The observation group showed significantly better postoperative QoL outcomes in the domains of physical functioning, emotional functioning, physical symptoms, global health status, and overall QoL compared to the control group (all P<0.05). Regarding treatment adherence, the observation group demonstrated superior performance in daily activity duration, use of a respiratory trainer, and adherence to coughing exercises compared to the control group (all P<0.001). The duration of chest tube indwelling was significantly shorter in the observation group (P<0.001). Furthermore, the observation group showed better recovery in albumin and hemoglobin levels (both P<0.05). ConclusionA combined telephone and WeChat follow-up approach can significantly improve the QoL and treatment adherence for patients discharged with an indwelling drainage tube. This method effectively shortens the duration of postoperative tube drainage, promotes nutritional recovery, and accelerates overall postoperative rehabilitation.

Effect of Acupuncture on Postoperative Pain after Operation of Hemorrhoids and Fistula

【摘要】　目的　观察针刺法在治疗痔瘘术后疼痛的临床疗效。　方法　2009年1-6月，将符合纳入标准的93例痔瘘术后中度疼痛患者，随机分为治疗组49例与对照组44例。治疗组采用针刺治疗术后疼痛；对照组采用口服莫比可治疗术后疼痛，观察两组患者疼痛的消除程度。　结果　消除疼痛有效率治疗组为91.83%，对照组为68.18%，治疗组镇痛效果与对照组比较，差异有统计学意义（Plt;0.05）。　结论　痔瘘术后应用针刺法止痛效果好，有良好的临床应用前景。【Abstract】　Objective　To determine the effect of acupuncture on the treatment of pain after hemorrhoids and fistula operation.　Methods　Ninety-three participants who suffered from moderate pain after hemorrhoids and fistula operation in the West China Hospital of Sichuan University from January to June 2008 were enrolled prospectively and randomly assigned into treatment group (n=49) and control group (n=44). The treatment group was treated with acupuncture for postoperative pain relief, whilst Mobic was given orally to the control group. Relief degrees of pain in both groups were observed.　Results　Efficient power of pain relief was significantly higher in the treatment group compared with the control group (91.83% vs. 68.18%,Plt;0.05).　Conclusion　Application procedure of acupuncture can significantly relieve postoperative pain after hemorrhoids and fistula operation, which has a good prospect in clinical application.

英夫利昔单抗治疗难治性溃疡性结肠炎疗效观察

目的观察英夫利昔单抗治疗难治性溃疡性结肠炎的疗效。 方法将2010年2月－2012年5月收治的70例难治性溃疡性结肠炎患者随机分为治疗组和对照组，每组各35例。两组均给予常规治疗（复方谷氨酰胺、双歧杆菌三联活菌、泼尼松等），治疗组在常规治疗的基础上给予英夫利昔单抗5 mg/（kg·d）加入生理盐水100 mL于2 h内滴完，于治疗起始、第2周、第6周应用，随后每隔8周给予相同剂量以维持缓解，疗程为1年；对照组在常规治疗的基础上给予硫唑嘌呤1.5～2.0 mg/（kg·d）、1次/d口服治疗。 结果治疗组总有效率94.2%，对照组总有效率62.8%，差异有统计学意义（χ2=10.267，P=0.001）。两组均未出现明显不良反应。 结论英夫利昔单抗治疗难治性溃疡性结肠炎具有较好的疗效，无明显不良反应。

The Clinical Efficacy of Total Glucosides of Peony in the Treatment of Primary Sjögren’s Syndrome

目的　观察白芍总苷治疗原发性干燥综合征的疗效及不良反应。 方法　收集2008年1月－2012年1月诊断的原发性干燥综合征患者48例，使其口服白芍总苷0.3～0.6 g，3次/d，疗程6个月，对比治疗前后患者的临床症状及唾液腺功能（唾液腺核素显像定量分析）改善情况、泪液分泌试验（Schirmer试验）、血沉、C反应蛋白、血清γ球蛋白（采用琼脂糖凝胶电泳法）的改善情况，并记录可能的不良反应。 结果　经过6个月的治疗，患者的临床症状、血沉、C反应蛋白、血清γ球蛋白等方面情况有所改善，差异有统计学意义（P＜0.05）。但唾液腺功能、Schirmer试验改善不明显，差异无统计学意义（P＞0.05）。 结论　白芍总苷在改善原发性干燥综合征临床症状及实验室指标疗效好，不良反应少，但在改善唾液腺功能及泪腺功能疗效欠佳。

Efficacy of Tazarotene Cream in the Treatment of Acne Vulgaris

摘要:目的: 观察01%他扎罗汀乳膏(乐为)治疗寻常型痤疮的临床疗效和安全性。 方法 :以轻中度痤疮患者40例,随机分为治疗组20例,外用01%他扎罗汀乳膏每晚1次,连用4周;对照组20例,外用01%维A酸霜每晚1次,连用4周,停药后观察疗效。 结果 : 治疗组基愈8例,显效7例,总有效率75%; 对照组基愈5例,显效6例,总有效率55%。两组结果经统计学处理,差异有显著性,P lt;005。 结论 : 他扎罗汀乳膏治疗寻常型痤疮安全、有效。Abstract: Objective: To evaluate the efficacy and safety of 01% Tazarotene Cream (Tazhaluoting Rugao)in the treatment of acne vulgaris. Methods : 40 patients, diagnosed clinically to have mild to moderate acne vulgaris were randomly and averagely assigned to two groups. 01% Tazarotene Cream and 01%Tretinoin Cream were used respectively daily night for 4 weeks on these two groups. Observe the efficacy after the ointment withdrawal. Results : 8 patients were basically cured and 7 improved in the experiment group, the total effective rate was 750%. 5 patients were basically cured and 6 improved in the control group, the total effective rate was 550%. There is significant difference between these two groups statistically (P lt;005). Conclusion : Tazarotene Cream is quite effective and safe in the treatment of acne vulgaris.

超声电导仪治疗急性胰腺炎疼痛的疗效观察

目的观察超声电导仪导入专用止痛凝胶片对急性胰腺炎腹部疼痛的止痛疗效。 方法2013年3月－5月收治的40例急性胰腺炎患者随机分为治疗组和对照组各20例，两组均采用常规治疗及护理，治疗组在此基础上加用床旁超声电导仪导入止痛药贴，观察其疗效及疼痛评分的变化。 结果两组患者在治疗第1天疼痛测值差异无统计学意义（P＞0.05），在持续治疗3、5、7 d后疼痛测值差异有统计学意义（P＜0.05），治疗组止痛效果明显优于对照组。治疗组由于疼痛缓解，18例患者能自行在床上翻身，对照组仅12例可自行在床上翻身，差异有统计学意义（χ2=4.800，P=0.028）；治疗组15例患者睡眠情况良好，对照组仅6例睡眠良好，差异有统计学意义（χ2=8.120，P=0.004）。 结论超声电导仪导入止痛药贴对急性胰腺炎腹部疼痛的止痛效果明显。

Thera Peutic Observation on 32 Cases of Gastritis Verrucosa Treated by Radiofrequency under the Guidance of Endoscopy Combined with Drugs

目的：探讨射频配合药物治疗疣状胃炎的疗效。方法:将胃镜诊断为疣状胃炎患者68例随机分为两组，射频配合药物治疗组用射频波25～40W对病灶行一次性“ 烧灼”，术后口服奥美拉唑胶囊4周；药物治疗组使用奥美拉唑治疗4周组作为对照组。两组若幽门螺杆菌(HP)阳性者均给予根除HP治疗。结果：射频配合药物治疗组症状缓解/消失率及疣状病灶消退率明显优于药物治疗组（P＜0.01）。结论：射频配合药物治疗疣状胃炎是一种较理想的、值得推广的有效方法，具有治疗彻底，操作技术简单,使用安全,病灶愈合快,治愈时间短,价格便宜,病人痛苦小等优点。

先天性桡骨发育过长伴马蹄内翻足综合康复治疗一例

Comparison on the treatment of proliferative diabetic retinopathy with ranibizumab and conbercept adjuvant for pars plana vitrectomy

Objective To compare the outcomes of ranibizumab and conbercept adjunct for pars plana vitrectomy (PPV) in the treatment of proliferative diabetic retinopathy (PDR). MethodsA prospective randomized case-control study. From June 2022 to December 2023, 90 cases (90 eyes) of PDR patients diagnosed through ophthalmic examination at Department of Ophthalmology of Gansu Provincial Hospital were included in the study. All patients underwent the best corrected visual acuity (BCVA), intraocular pressure, B-mode ultrasound, and optical coherence tomography (OCT) examinations. The central macular thickness (CMT) was measured using an OCT instrument. The patients were randomly divided into a intravitreal injection of ranibizumab group (monoclonal-antibody group) and a intravitreal injection of conbercept group (fusion-protein group) using a random number table method, with 45 cases (45 eyes) in each group. Two groups of patients were intravitreal injected with 10 mg/ml ranibizumab or conbercept 0.05 ml, respectively. A standard 23G PPV was performed through the flat part of the ciliary body 3-7 days after intravitreal injection. Relevant examinations were performed using the same equipments and methods as before surgery at postoperative 1 week, 1, 3, 6, and 12 months. The PPV time, intraoperative use of intraocular electrocoagulation, incidence of iatrogenic retinal breaks, and sterile air or silicone oil tamponade rate in the vitreous cavity, the postoperative changes of BCVA and CMT, and incidence of complications were compared between two groups. Independent sample t test was used for inter group comparison. ResultsThe intraoperative utilization rate of intraocular electrocoagulation in the monoclonal-antibody group was higher than that in the fusion-protein group, and the difference was statistically significant (χ2=3.876, P＜0.05). There were no statistically significant differences in the PPV time (t=0.152), intraoperative bleeding rate (χ2=0.800), incidence of iatrogenic retinal breaks (χ2=1.975), and sterile air and silicone oil tamponade rate in the vitreous cavity (χ2=1.607, 1.553) between the two groups (P＞0.05). There were no statistically significant differences in early and late postoperative vitreous hemorrhage (χ2=1.235, 2.355), and re-PPV (χ2=2.355) between two groups (P＞0.05). The BCVA of the fusion-protein group was significantly better than that of the monoclonal-antibody group at postoperative 3 months, and the difference was statistically significant (t=2.428, P＜0.05). The CMT of the fusion-protein group was lower than that in the monoclonal-antibody group at postoperative 1 week, and the difference was statistically significant (t=2.739, P＜0.05). None of the patients experienced endophthalmitis, retinal artery occlusion, or severe cardiovascular events after surgery. ConclusionCompared with intravitreal injection of ranibizumab before PPV, intravitreal injection of conbercept before PPV in PDR patients can shorten the surgical time, reduce intraoperative bleeding rate, lower the rate of electrocoagulation and intraocular tamponade, and incidence of iatrogenic retinal breaks, and improve the visual acuity.