Objective To investigate the current situation, problems of medicinal biotechnology in China, and to provide the relevant countermeasures for its development. Methods We surveyed the units which could carry out medicinal biotechnology projects in 30 provinces except Tibet, and compared the results with that in America.Results The questionnaire were returned from 25 provinces (83.4%), and there were 1 477 medicinal biotechnology projects carried out by 149 units in the past 10 years. These projects ranged from basic biotechnology to regenerative medicine and stem cell researches. The basic research projects constituted quite large percentage among all the projects. But the development levels in different areas were imbalanced, cross correlation with the development levels of economy. An echelon team of talents has been developed, most of them were trained in China. The invested capital differed considerably among units, in general the amounts were insufficient. Most invested capital came from the government. The number of patent application for projects based on independent-developed technology was small. This showed that project principals had a poor understanding of patents. More than half of units did not have a Bioethics Committee. From the search result for documents, the number of articles on stem research of China was close to that in America; and the number of articles on gene treatment and tissue engineering has already exceeded that of America. However, research on gene diagnosis of China was lagging far behind America. Conclusions An echelon team of talents has been developed, most of them are trained in China.We should give full play to the advantage of the distribution of qualified personal resources in developed economical areas so as to promote the applicability and popularity of medicinal biotechnology in less developed areas.Regarding to applicability and development, we should first develop applied technology to form the core competetiveness of basic research, technology development and application; we should also strengthen the training in ethics and regulation to establish a set of scientific assessment of medicinal biotechnology and management system.
ObjectiveTo investigate the current status of the promotion of appropriate health technologies in Zhejiang province from 2009 to 2013, in order to provide baseline data for appropriate health technologies, application and research. MethodsThe status of promotion of appropriate health technologies in different regions of Zhejiang province were quantitatively described and compared according to the information in the websites of The Application and Promotion of Appropriate Techniques of Health, The Application and Promotion of Appropriate Techniques of Traditional Chinese Medicine as well as the Bank of Appropriate Technologies. Resultsa) A total of 127 Model Bases of Appropriate Health Technologies were set up, which were combined 127 leading institutions and 513 joint units, covering 11 cities, 40 counties, and 206 townships. b) The type of first aid base and chronic diseases base accounted for 33.0% and 25.3% of total types of model bases respectively; however, the number of bases dealing with rehabilitation care, public health and diseases referred to Ophthalmology & Otolaryngology and skin disease were very small. c) There were 486 appropriate health technologies promoted in Zhejiang province; appropriate technology about first aid, chronic diseases, women and children, rehabilitation care, public health, Ophthalmology & Otolaryngology and skin disease, traditional Chinese medicine and family planning accounted for 26.5%, 18.9%, 17.9%, 11.0%, 10.6%, 7.6%, 4.6% and 1.4%, respectively of total types of appropriate health technologies. d) The numbers of appropriate health technologies promoted in different regions were varied. Most of appropriate health technologies were promoted in more developed regions or more regions rich in health resources. Conclusiona) The model of "1+X" is used to promote the application of appropriate health technologies in Zhejiang province, and the prefecture-level regions of Zhejiang province have established the Model Bases of Appropriate Health Technologies in 11 cities. The promotion system of appropriate health technology is constructed and it achieves good results. b) In nine model bases, the most types of promotion bases are chronic diseases and first aid, and the technologies about first aid, chronic diseases, women and children are most promoted. c) The types of appropriate health technologies promoted in different areas are varied. d) It is necessary to evaluate and select appropriate health technology bases according to the burden of local disease and evidence.
Total hip arthroplasty is an end-stage treatment for hip diseases such as hip osteoarthritis and osteonecrosis of the femoral head. Traditional surgery models are still mostly used in China, and related day surgery models abroad have shown that day surgery for total hip arthroplasty is as safe and feasible as traditional pattern without increase in complications and readmission. It can also shorten the length of hospitalization for patients, reduce hospitalization costs, thereby speeding up bed turnover and increasing the utilization of medical resources. This article reviews the patient admission, perioperative management, anesthesia and surgical techniques, post-discharge rehabilitation and nursing care of patients undergoing day surgery for total hip arthroplasty, and aims to providea reference for the development of day surgery for total hip arthroplasty in China.
Esophageal carcinoma is a malignant tumor with high morbidity and mortality worldwide, and surgery is the main treatment currently. With the development of patient-centered care, the effect of surgery should not be limited to the improvement of the incidence of postoperative complications, mortality and other indicators. It is also important to provide experience related to disease and surgery from the perspective of patients. Therefore, more and more attention is paid to patient-reported outcomes by scholars. This paper will provide an overview of the international widely used, reliable and effective scales and researches about patient-reported outcomes in esophageal carcinoma.
Objective To understand the urination of orthopedic patients after the catheter is removed, and to explore the influencing factors of urodynia. Methods Convenient sampling was used to select 160 patients who underwent surgical treatment in the Department of Orthopedics of West China Hospital of Sichuan University from May to July 2020. Questionnaires were used to investigate the patients’ urination, and a logistic regression model was used to analyze the factors affecting the patients’ urodynia. Results A total of 157 patients urinated by themselves after the catheter was removed, with 102 cases of dysuria. Logistic regression results showed that male [odds ratio (OR)=0.282, 95% confidence interval (CI) (0.092, 0.863), P=0.027], Huaxi Emotional-Distress Index score [OR=1.407, 95%CI (1.124, 1.760), P=0.003] and intraoperative fluid infusion [OR=1.001, 95%CI (1.000, 1.002), P=0.014] were the influencing factors of urodynia. Conclusion Most orthopedic patients can urinate on their own after the catheter is removed, but more than half of the patients experience urodynia during the first urination. Gender, mental status and intraoperative fluid infusion are the influencing factors of urodynia after urinary catheter removal after surgery. Clinical nursing staff should identify these influencing factors as soon as possible and carry out targeted interventions to improve the success rate of patients with urination after removing the catheter, reduce the incidence of urodynia, and promote the recovery of patients.
Totally thoracoscopic surgery is a branch of minimally invasive cardiac surgeries, and its operational indicators are expanding with the development of the medical and imaging devices compared with median sternotomy and other minimally invasive cardiac surgeries (such as thoracoscope-assisted small incision surgery and robotic surgery). The learning curve is significantly shortened through the professional technique training. Totally thoracoscopic cardiac surgery has many advantages, such as minor trauma, few serious complications, fast recovery, high patient acceptance and being suitable to our country's current situation. Therefore it will be one main direction of minimally invasive cardiac surgery. This article mainly introduced the current status of totally thoracoscopic technology in the field of cardiac surgery in China.
Objective To investigate the current status of multi-disciplinary team (MDT) in outpatient clinics of medical institutions in Sichuan, and to provide reference for further promoting the MDT model in outpatient clinics. Methods In November 2022, questionnaires were distributed to the outpatient management personnel of Sichuan Outpatient Management and Medical Quality Control Center from various medical institutions. The questionnaire included the basic information of the survey subjects and medical institutions, the current status of outpatient MDT work, the current status of operation and management, and the internal and external influencing factors of MDT development. Results A total of 106 questionnaires were received, of which 104 were valid. There were 70 hospitals that had provided outpatient MDT services, with a development rate of 67.31%, mainly concentrated in the past 5 years. A total of 60 hospitals (85.71%) had established MDT related systems, but only 14 hospitals (20.00%) had carried out relevant quality evaluation work. Among the 104 outpatient management personnel surveyed, 83.65% believed that the external factor affecting the development of outpatient MDT was the lack of correct understanding of MDT by patients, and 78.85% believed that the internal factor affecting the development of outpatient MDT was the low participation enthusiasm of departments and doctors. Conclusions The outpatient MDT in Sichuan is still in its early stages of development, and the outpatient MDT model has not yet been unified in terms of establishment standards, organizational methods, operational management, and fee standards. In the future, relevant departments and medical institutions still need to work together to promote its sustainable development.