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find Keyword "感染" 1019 results
  • 关节镜下前交叉韧带重建术后早期感染三例

    目的 报道 3 例关节镜下前交叉韧带重建术后早期感染患者临床资料,总结治疗方法及疗效,分析预防措施。 方法 2015 年 3 月—2017 年 3 月,关节镜下前交叉韧带重建术后 3 例发生早期感染。其中男 2 例,女 1 例;年龄 30、39、32 岁。术后 7 d 出现膝关节疼痛伴低热症状,均存在关节腔积液,其中 1 例积液细菌培养呈阳性;白细胞计数及中性粒细胞计数在正常范围,超敏 C-反应蛋白及红细胞沉降率升高。2 例给予万古霉素、1 例给予关节镜下关节腔清理术后治愈。 结果 3 例患者经抗感染治疗后,临床症状及体征均消失,感染治愈;白细胞计数及中性粒细胞计数、超敏 C-反应蛋白、红细胞沉降率均在正常范围。术后 90 d 膝关节 Lysholm 评分为 89、88、80 分。 结论 关节镜下前交叉韧带重建术后早期感染的发生可能与手术时间延长及关节腔积液有关,经长期口服利福平抗感染治疗后可获较好临床疗效。

    Release date:2018-02-07 03:21 Export PDF Favorites Scan
  • 充填式无张力疝修补术后网塞感染的探讨及处理

    Release date:2016-09-01 09:30 Export PDF Favorites Scan
  • Logistic Regression Analysis of Risk Factors for Surgical Site Infection after Hepatobili-ary and Pancreatic Surgery

    Objective To study the influence factors of surgical site infection (SSI) after hepatobiliary and pancreatic surgery. Methods Fifty patients suffered from SSI after hepatobiliary and pancreatic surgery who treated in Feng,nan District Hospital of Tangshan City from April 2010 and April 2015 were retrospectively collected as observation group, and 102 patients who didn’t suffered from SSI after hepatobiliary and pancreatic surgery at the same time period were retrospectively collected as control group. Then logistic regression was performed to explore the influence factors of SSI. Results Results of univariate analysis showed that, the ratios of patients older than 60 years, combined with cardiovascular and cerebrovascular diseases, had abdominal surgery history, had smoking history, suffered from the increased level of preoperative blood glucose , suffered from preoperative infection, operative time was longer than 180 minutes, American Societyof Anesthesiologists (ASA) score were 3-5, indwelled drainage tube, without dressing changes within 48 hours after surgery, and new injury severity score (NISS) were 2-3 were higher in observation group (P<0.05). Results of logistic regression analysis showed that, patients had history of abdominal surgery (OR=1.92), without dressing changes within 48 hours after surgery (OR=2.07), and NISS were 2-3 (OR=2.27) had higher incidence of SSI (P<0.05). Conclusion We should pay more attention on the patient with abdominal surgery history and with NISS of 2-3, and give dressing changes within 48 hours after surgery, to reduce the incidence of SSI.

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  • Diagnosis, treatment and prevention of cardiac implantable electronic device infection

    Cardiac implantable electronic device (CIED) is commonly used to treat arrhythmias. The amount of CIED implantation has increased year by year since its first application in 1958. At the same time, the CIED infection rate also increases significantly. Although the infection rate is very low for the primary implantation, the consequences of CIED infection are serious, and it is often necessary to remove the equipment for treatment. The mortality rate in patients with CIED infections is high, and the economic burden is huge. In this paper, the epidemiology, pathogenesis and pathogen, manifestations and diagnosis, risk factors, treatment and preventive measures of CIED infection were systematically described based on the recently published guidelines and international consensus literature, so as to provide theoretical guidance for the prevention of CIED infections.

    Release date:2021-04-15 05:32 Export PDF Favorites Scan
  • The Clinical Application of Bronchoalveolar Lavage by Way of Fibrobronchoscopy on Patients with Pulmonary Infection

    目的:探讨纤维支气管镜(简称纤支镜)肺泡灌洗术在治疗肺部感染性疾病的疗效。方法:共从内科系统中入选社区获得性肺炎和医院获得性肺炎患者122例,将其分为二组,治疗组:传统治疗加纤支镜肺泡灌洗术治疗肺部感染,共52例;对照组:传统方法治疗肺部感染,共70例。结果:两组病例在发热时间,咳嗽,咳痰及肺部罗音消失时间,住院日,抗生素使用时间,治愈率和死亡率方面对比均有显著性差异(Plt;0.05)。结论:纤支镜肺泡灌洗术在治疗肺部感染性疾病的疗效确切,且术中危险性小,值得推广。

    Release date:2016-09-08 09:56 Export PDF Favorites Scan
  • Good综合征合并新型冠状病毒持续感染、肺腺癌一例并文献复习

    目的 通过本病例及文献复习以增加对Good综合征合并新型冠状病毒感染(coronavirus disease 2019,COVID-19)及免疫缺陷与肿瘤发生的认知,为Good综合征合并COVID-19的治疗提供参考。方法 回顾我院诊治的1例Good综合征合并新型冠状病毒(新冠病毒)持续感染、肺腺癌患者的临床资料,复习既往Good综合征合并COVID-19相关文献,总结其临床特征及治疗方法。结果 患者男,61岁,反复发热、咳嗽6个月余。胸部CT提示双肺多发炎症,右肺上叶前段胸膜下混合磨玻璃结节,前纵隔肿块;新冠病毒核酸检测阳性,新冠病毒IgG+IgM抗体检测阴性。给予康复期血浆疗法后患者明显好转,核酸检测呈阴性,抗体检测呈阳性,后于我院手术切除纵隔及肺部病变,最终明确诊断为Good综合征合并浸润性肺腺癌。复习文献,共有17例Good综合征合并COVID-19个案报道,男性相较于女性发病率更高,胸腺瘤主要病理类型为AB型(55.6%),大部分患者给予了免疫球蛋白治疗,但仍有7例患者死亡,死亡原因大多为呼吸衰竭、脓毒性休克。结论 对于有胸腺瘤病史伴反复感染的患者临床医生应想到Good综合征的可能,早诊断早治疗,同时对存在免疫缺陷、胸腺瘤的患者要警惕恶性肿瘤的发生。

    Release date:2025-03-25 01:25 Export PDF Favorites Scan
  • EFFECT OF ANTI-INFECTIVE RECONSTITUTED BONE XENOGRAFT AS PRIMARY BONE GRAFTING ON REPAIR OF CONTAMINATED RADIUS DEFECT IN CANINE

    Objective To investigate the effect of anti-infective reconstitutedbone xenograft (ARBX) as primary grafting on repair of a segmental contaminateddefect in canine radius. Methods The contaminated segmentaldefects of 1.5 cm were made in both radius of 8 canine and 1 ml of staphylococal suspension was injected into the defect region at a concentration of 5×106 CFU/ml. ARBX(experimental side) or RBX(control side) was implanted into the two sides of the defects respectively as primary grafting followed by internal fixation. The results were compared between the two grafting materials in repairing the contaminated segmental defect. Results In ARBX side, the defects were repaired completely in 5 cases and partially in 1 case, and there existed no osteomyelitis in all cases; while in RBX side, the defects were repaired partially in 1 case and were not repaired in 5 cases after 6 months of operation, and there existed osteomyelitis in all cases. Conclusion Besides its b osteoinductive and osteoconductive activity, ARBX is highly antibacterial and can be used as primary grafting in repairing contaminated segmental defects.

    Release date:2016-09-01 09:33 Export PDF Favorites Scan
  • 新型冠状病毒感染伴发癫痫及其发病机制与脑电图改变

    新型冠状病毒感染(Corona virus disease 2019,COVID-19)是一种由冠状病毒(SARS-CoV-2)导致的新型传染性疾病。关于COVID-19与癫痫之间的关系,有研究认为癫痫发作和COVID-19无明显关系;但也有不少学者认为,癫痫发作是COVID-19的继发症状,甚至是早期症状。COVID-19患者中癫痫发作发生率为0.08%~1.9%。COVID-19出现癫痫发作的直接发病机制是,SARS-COV-2能够直接进入并感染中枢神经系统,引起脑膜炎和脑炎,从而引起癫痫发作。间接发病机制包括:中枢神经系统炎症(细胞因子风暴)、血-脑屏障的破坏、凝血异常、脑卒中、线粒体功能异常、电解质紊乱。新发作和频发癫痫发作的患者可能导致预后更差,死亡率更高。COVID-19伴发癫痫患者中脑电图(Electroencephalogram,EEG)改变的主要表现为:基本节律不同程度的慢化、节律性慢活动、癫痫样放电(包括周期性放电和散在性棘波、尖波等)。癫痫患者EEG的异常部位主要分布在额叶,然而,异常EEG表现并无特异性。

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  • 感染性休克时液体复苏相关性肺损伤研究进展

    在过去10 年里, 随着人口老龄化, 全身性感染的发病率不断增长, 全球每年约1800 万人罹患严重感染, 而感染性休克的病死率高达30% ~60% [ 1 ] 。感染性休克治疗中液体复苏被作为最基本、最重要的原则, 早期液体复苏是治疗感染性休克的重要措施之一。但液体复苏在恢复有效循环血量的同时,也有可能会导致肺水肿加重及液体复苏相关性肺损伤。

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  • 多药耐药革兰阴性菌肺炎的抗感染治疗

    铜绿假单胞菌、鲍曼不动杆菌和肺炎克雷伯菌是最容易产生对多种抗生素耐药的院内致病菌。耐甲氧西林金黄色葡萄球菌(MRSA)和耐万古霉素肠球菌(VRE)的定义相对简单,只要对一种有代表性的抗生素产生耐药就可以了。但是,给多药耐药或者泛耐药的革兰阴性杆菌下定义则较为困难 ]。一般来讲,如果对下列5种抗生素中两种以上耐药称为多药耐药:包括对铜绿假单胞菌有活性的头孢菌素类、碳青霉烯类、加酶抑制剂的B一内酰胺类;对铜绿假单胞菌有活性的氟喹诺酮类、氨基糖苷类。如果仅对多黏菌素敏感,但是对目前所有的抗生素都耐药则称为泛耐药(Pandrug—resistant)。一方面,多药耐药或泛耐药的革兰阴性菌感染逐渐增多;另一方面,许多大的制药企业逐渐放弃了新抗生素的研发,尤其是针对革兰阴性菌的抗生素研发更少。人们惊呼:后抗生素时代(post—antibiotic era)真的来临了吗 7我们如何应对?

    Release date:2016-09-14 11:52 Export PDF Favorites Scan
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