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find Keyword "心脏瓣膜手术" 16 results
  • A wearable six-minute walk-based system to predict postoperative pulmonary complications after cardiac valve surgery: an exploratory study

    In recent years, wearable devices have seen a booming development, and the integration of wearable devices with clinical settings is an important direction in the development of wearable devices. The purpose of this study is to establish a prediction model for postoperative pulmonary complications (PPCs) by continuously monitoring respiratory physiological parameters of cardiac valve surgery patients during the preoperative 6-Minute Walk Test (6MWT) with a wearable device. By enrolling 53 patients with cardiac valve diseases in the Department of Cardiovascular Surgery, West China Hospital, Sichuan University, the grouping was based on the presence or absence of PPCs in the postoperative period. The 6MWT continuous respiratory physiological parameters collected by the SensEcho wearable device were analyzed, and the group differences in respiratory parameters and oxygen saturation parameters were calculated, and a prediction model was constructed. The results showed that continuous monitoring of respiratory physiological parameters in 6MWT using a wearable device had a better predictive trend for PPCs in cardiac valve surgery patients, providing a novel reference model for integrating wearable devices with the clinic.

    Release date:2023-12-21 03:53 Export PDF Favorites Scan
  • Combined Cardiac Valve Surgery and Coronary Artery Bypass Grafting: Report of 81 Cases

    Objective To retrospectively review the clinical experience and early surgical results of combined cardiac valve surgery and coronary artery bypass grafting (CABG). Methods From Jan. 2000 to Dec. 2005, combined valve surgery and CABG was performed in 81 patients. 37 patients were rheumatic heart disease with coronary stenosis, and 44 patients were coronary artery disease with valvular dysfunction. Single vessel disease was in 18 patients, two vessels disease in 9 and triple-vessel disease in 54. All the patients received sternotomy and combined valve surgery and CABG under cardiopulmonary bypass. Mitral valve repair and CABG were done in 26 patients. Valve replacement and CABG were done in 55 patients with 49 mechanical valves and 16 tissue valves. Four patients had left ventricular aneurysm resection concomitantly. The number of distal anastomosis was 3.12 5= 1.51 with 66 left internal mammary arteries bypassed to left anterior descending. Post-operative intra-aortic balloon pump was required in 4 cases for low cardiac output syndrome. Results Two patients died of low cardiac output syndrome with multiple organs failure. 79 patients had smooth recovery and discharged from hospital with improved heart function. 64 patients had completed follow-up with 5 late non cardiac related death in a mean follow-up period of 14.2 months. Conclusion Combined one stage valve surgery and CABG is effective with acceptable morbidity and mortality.

    Release date:2016-08-30 06:22 Export PDF Favorites Scan
  • Establishment of a Risk Prediction Model and Risk Score for Inhospital Mortality after Heart Valve Surgery

    Abstract: Objective To establish a risk prediction model and risk score for inhospital mortality in heart valve surgery patients, in order to promote its perioperative safety. Methods We collected records of 4 032 consecutive patients who underwent aortic valve replacement, mitral valve repair, mitral valve replacement, or aortic and mitral combination procedure in Changhai hospital from January 1,1998 to December 31,2008. Their average age was 45.90±13.60 years and included 1 876 (46.53%) males and 2 156 (53.57%) females. Based on the valve operated on, we divided the patients into three groups including mitral valve surgery group (n=1 910), aortic valve surgery group (n=724), and mitral plus aortic valve surgery group (n=1 398). The population was divided a 60% development sample (n=2 418) and a 40% validation sample (n=1 614). We identified potential risk factors, conducted univariate analysis and multifactor logistic regression to determine the independent risk factors and set up a risk model. The calibration and discrimination of the model were assessed by the HosmerLemeshow (H-L) test and [CM(159mm]the area under the receiver operating characteristic (ROC) curve,respectively. We finally produced a risk score according to the coefficient β and rank of variables in the logistic regression model. Results The general inhospital mortality of the whole group was 4.74% (191/4 032). The results of multifactor logistic regression analysis showed that eight variables including tricuspid valve incompetence with OR=1.33 and 95%CI 1.071 to 1.648, arotic valve stenosis with OR=1.34 and 95%CI 1.082 to 1.659, chronic lung disease with OR=2.11 and 95%CI 1.292 to 3.455, left ventricular ejection fraction with OR=1.55 and 95%CI 1.081 to 2.234, critical preoperative status with OR=2.69 and 95%CI 1.499 to 4.821, NYHA ⅢⅣ (New York Heart Association) with OR=2.75 and 95%CI 1.343 to 5641, concomitant coronary artery bypass graft surgery (CABG) with OR=3.02 and 95%CI 1.405 to 6.483, and serum creatinine just before surgery with OR=4.16 and 95%CI 1.979 to 8.766 were independently correlated with inhospital mortality. Our risk model showed good calibration and discriminative power for all the groups. P values of H-L test were all higher than 0.05 (development sample: χ2=1.615, P=0.830, validation sample: χ2=2.218, P=0.200, mitral valve surgery sample: χ2=5.175,P=0.470, aortic valve surgery sample: χ2=12.708, P=0.090, mitral plus aortic valve surgery sample: χ2=3.875, P=0.380), and the areas under the ROC curve were all larger than 0.70 (development sample: 0.757 with 95%CI 0.712 to 0.802, validation sample: 0.754 and 95%CI 0.701 to 0806; mitral valve surgery sample: 0.760 and 95%CI 0.706 to 0.813, aortic valve surgery sample: 0.803 and 95%CI 0.738 to 0.868, mitral plus aortic valve surgery sample: 0.727 and 95%CI 0.668 to 0.785). The risk score was successfully established: tricuspid valve regurgitation (mild:1 point, moderate: 2 points, severe:3 points), arotic valve stenosis (mild: 1 point, moderate: 2 points, severe: 3 points), chronic lung disease (3 points), left ventricular ejection fraction (40% to 50%: 2 points, 30% to 40%: 4 points, <30%: 6 points), critical preoperative status (3 points), NYHA IIIIV (4 points), concomitant CABG (4 points), and serum creatinine (>110 μmol/L: 5 points).Conclusion  Eight risk factors including tricuspid valve regurgitation are independent risk factors associated with inhospital mortality of heart valve surgery patients in China. The established risk model and risk score have good calibration and discrimination in predicting inhospital mortality of heart valve surgery patients.

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  • Predictive Risk Factors for Postoperative Respiratory Failure in Patients Undergoing Valvular Surgery

    Abstract: Objective To analyze risk factors associated with postoperative respiratory failure in patients with valvular surgery. Methods Between January 2001 and November 2010, clinical data of 618 patients with 339 males and 279 fameles at age of 10-74(44.01±13.95)years,undergoing valvular operations were investigated retrospectively. We divided the patients into two groups according to the presence (74 patients)or absence(544 patients)of postoperative respiratory failure. Its risk factors were evaluated by univariate and multivariate logistic regression analysis. Results The hospital mortality rate of valvular surgery was 6.1%(38/618).The morbidity rate of respiratory failure was 12.0%(74/618) with hospital mortality rate at 17.6%(13/74) which was significantly higher than those patients without postoperative respiratory failure at 4.6%(25/544, χ2=18.994, P=0.000). Univariate analysis showed age> 65 years(P=0.005), New York Heart Association(NYHA)classⅣ(P=0.014), election fraction< 50.0%(P=0.003), cardiopulmonary bypass time> 3 h(P=0.001), aortic cross clamping time> 2 h(P=0.008), concomitant operation( valvular operation with coronary artery bypass grafting, Bentall or radiofrequency ablation maze operation(P=0.000), reoperation(P=0.012), postoperative complications (P=0.000), and blood transfusion> 2 000 ml(P=0.000) were important risk factors for postoperative respiratory failure. Multivariate logistic regression showed that concomitant operation(P=0.003), reoperation(P=0.010), postoperative complications(P=0.000), and blood transfusion>2 000 ml(P=0.012)were significant independent predictive risk factors. Conclusion This study suggest that patients with predictive risk factors of postoperative respiratory failure need more carefully treated. The morbidity of these patients would be reduced through improving perioperative management, shortening cardiopulmonary bypass time and reducing postoperative complications.

    Release date:2016-08-30 05:49 Export PDF Favorites Scan
  • Risk Factors of Secondary Tricuspid Regurgitation: A Meta-Analysis

    Objective To analyze and explore the risk factors of secondary tricuspid regurgitation (TR) after left-sided valve surgery (left cardiac valve replacement or valvuloplasty) using meta-analysis, so as to provide evidence for clinical diagnosis and treatment of secondary TR. Methods We electronically searched databases including PubMed, MEDLINE, CBM, CNKI, VIP, for literature on the risk factors of secondary TR after left-sided valve surgery from 1995 to 2012. According to the inclusion and exclusion criteria, we screened literature, extracted data, and assessed methodological quality. Then, meta-analysis was performed using RevMan 5.0 software. Results A total of 6 case-control studies were included, involving 437 patients and 2 102 controls. The results of meta-analysis showed that, the risk factors of progressive exacerbation of secondary TR after left-sided valve surgery included preoperative atrial fibrillation (OR=3.90, 95%CI 3.00 to 5.07; adjusted OR=3.04, 95%CI 2.21 to 4.16), age (MD=5.36, 95%CI 3.49 to 7.23), huge left atrium (OR=5.17, 95%CI 3.12 to 8.57; adjusted OR=1.91, 95%CI 1.49 to 2.44) or left atrium diameter (MD=4.85, 95%CI 3.18 to 6.53), degradation of left heart function (OR=2.97, 95%CI 1.73 to 5.08), rheumatic pathological change (OR=3.06, 95%CI 1.66 to 4.68), preoperative TR no less than 2+ (OR=3.52, 95%CI 1.26 to 9.89), and mitral valve replacement (MVR) (OR=2.35, 95%CI 1.68 to 3.30). Sex (OR=1.54, 95%CI 0.94 to 2.52) and preoperative pulmonary arterial hypertension (OR=1.28, 95%CI 0.77 to 2.12) were not associated with secondary TR after left-sided valve surgery. Conclusion The risk factors of progressive exacerbation of secondary TR after left-sided valve surgery include preoperative atrial fibrillation, age, huge left atrium or left atrium diameter, degradation of left heart function, rheumatic pathological change, preoperative TR no less than 2+, and MVR. Understanding these risk factors helps us to improve the long-time effectiveness of preventing and treating TR after left-sided valve surgery.

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  • 老年患者二尖瓣置换同期行冠状动脉旁路移植术的临床分析

    目的 总结老年二尖瓣疾病合并冠心病患者心瓣膜置换术同期行冠状动脉旁路移植术(CABG)的经验,以提高临床效果。 方法 2002年7月至2004年7月我科共30例老年二尖瓣疾病患者二尖瓣置换术同期行CABG。年龄66.0±9.1岁(60~73岁), 4例为风湿性瓣膜病变,26例为二尖瓣瓣膜退行性病变。术前心功能分级(NYHA):Ⅰ级3例,Ⅱ级5例,Ⅲ级17例,Ⅳ级5例。共移植旁路血管71支,使用左侧乳内动脉24例,其余均为大隐静脉。置换机械瓣27例,置换生物瓣3例;行三尖瓣De Vega成形术17例。 结果 术后早期死亡1例(3.3%)。随访29例,平均随访时间13个月,心功能均有明显改善,Ⅰ级18例,Ⅱ级10例,Ⅲ级1例,可从事简单的运动及正常家务劳动,生活质量满意。 结论 老年二尖瓣疾病患者二尖瓣置换术同期行CABG的危险性较大,充分的术前准备,正确的手术方案,术中良好的心肌保护及严密的术后处理是手术成功的重要因素。

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
  • Cryomaze ablation procedure for atrial fibrillation concomitant with valve surgery

    Objective To summarize safety and effectiveness of cryomaze ablation procedure concomitant with valve surgery. Methods We retrospectively investigated the clinical data of 62 patients (24 males and 38 females) with mean age of 49.4±14.2 years who underwent cryomaze ablation procedure concomitant with valve surgery in our hospital from August 2013 through July 2015. The heart rhythm of the patients after surgery was supervised by 12-leads electrical cardiogram respectively. Results The rate of sinus rhythm restored right after surgery was 98.4%. The rate of sinus rhythm restored at the time of discharge was 93.4%. The rate of sinus rhythm restored 3 months, 6 months, 12 months, 18 months after surgery was 90.2%, 87.3%, 85.0%, 83.3% respectively. The one-year post-operation rate of sinus rhythm restored for the group of right minimal invasive thoracoscopic assisted mitral valve surgery was 90.5%. Longer duration for atrial fibrillation (>7 years) was a risk factor for the reoccurrence of atrial fibrillation 1 year after surgery (P<0.05). Conclusion Cryomaze ablation procedure concomitant with valve surgery is quite effective in treatment of rheumatic valve disease and atrial fibrillation. This approach is associated with fewer complications, comparable atrial fibrillation reoccurrence for short-term follow-up.

    Release date:2017-04-24 03:51 Export PDF Favorites Scan
  • Perioperative results of cardiac valve surgery in patients with asymptomatic SARS-CoV-2 infection

    ObjectiveTo analyze the perioperative outcomes of cardiac valve surgery in patients with asymptomatic SARS-CoV-2 infection. MethodsThe perioperative clinical data of patients receiving heart valve replacement in the Department of Cardiovascular Surgery, the First Affiliated Hospital of University of Science and Technology of China from November 2022 to February 2023 were retrospectively analyzed. According to whether the patients were infected with SARS-CoV-2, they were divided into a non-infected group and an asymptomatic group. The perioperative data of the patients were compared between the two groups, and the effect of asymptomatic infection on the result of heart valve replacement surgery was analyzed. ResultsA total of 66 patients were enrolled including 36 males and 30 females with a mean age of 58.0±11.1 years. There were 51 patients in the non-infected group and 15 patients in the asymtomatic group. There were 2 patients of mitral valve replacement, 20 patients of aortic valve replacement, 1 patient of double valve replacement, 3 patients of aortic valve replacement with tricuspid valvoplasty, 22 patients of mitral valve replacement and tricuspid valvoplasty, 18 patients of double valve replacement and tricuspid valvoplasty. Asymptomatic infected patients received more emergency surgery than uninfected patients (26.7% vs. 0.0%, P<0.01). There was no statistical difference in the duration of extracorporeal circulation, aortic occlusion, mechanical ventilation time after the surgery, ICU stay, postoperative drainage volume, or postoperative complications between the two groups. ConclusionPerioperative results of cardiac valve surgery in patients with asymptomatic SARS-CoV-2 infection and non-infection are almost the same.

    Release date:2024-06-26 01:25 Export PDF Favorites Scan
  • Safety of the removal of pericardial and mediastinal drain within a different drainage volume after cardiac valvular replacement surgery: A case control study

    ObjectiveTo assess the safety of the removal of pericardial and mediastinal drain within different drainage volume after cardiac valvular replacement surgery.MethodsBetween July 2013 and July 2017, 201 patients with rheumatic heart disease (CHD) were treated with valve replacement in our hospital, including 57 males and 144 females, aged 15 to 72 years. They were divided into two groups according to the amount of 24-h drainage before the drain removal: a group one with 24-h drainage volume≤50 ml (n=127) and a group two with 24-h drainage volume>50 ml (n=74). The postoperative hospital stay and the incidence of severe complications between the two groups were compared.ResultsThere was no difference between the two groups in the baseline information or the incidence of severe pericardial effusion and tamponade, while the group two tended to have a shorter length of hospital stay after surgery (8.0 d vs. 7.5 d, P=0.013).ConclusionIn CHD patients undergoing valvular surgery, compared with a relatively low amount of drainage before the drain removal, drawing the tube at a greater amount of drainage (24-h drainage volume>50 ml) will shorten the length of hospital stay after cardiac surgery while incidence of severe complications remains the same.

    Release date:2019-01-03 04:52 Export PDF Favorites Scan
  • 先天性心脏病合并感染性心内膜炎的外科治疗

    目的 总结先天性心脏病(congenital heart disease,CHD)合并感染性心内膜炎(infective endocarditis,IE)的外科治疗经验,以提高诊断、治疗效果。 .方法 .回顾性分析我院73例CHD合并IE患者行瓣膜手术的临床资料,对30例主动脉瓣感染性心内膜炎者行主动脉瓣置换术,另3例行Ross手术。在IE累及二尖瓣21例患者中,行二尖瓣成形术5例,二尖瓣置换术16例;10例主动脉瓣、二尖瓣IE行双瓣膜置换术;对6例肺动脉瓣IE患者行单瓣法做肺动脉瓣成形术2例,肺动脉瓣置换术4例,其中1例同期行主动脉弓置换;3例三尖瓣IE均行三尖瓣置换术。结果 主动脉瓣感染33例(45.2%),二尖瓣感染21例(28.8%),肺动脉瓣感染6例(8.2%),双瓣膜感染10例(13.7%),三尖瓣感染3例(4.1%)。血培养及赘生物培养总阳性率为23.3%,其中链球菌8例(47.1%),葡萄球菌3例(17.6%)。本组无手术死亡,除1例二尖瓣置换术后1年再次发生IE,拒绝手术治疗外,其余72例患者随访1年均治愈。 结论 CHD应尽早行根治性手术,以避免远期并发IE,损坏心脏瓣膜。对CHD合并IE出现瓣膜关闭不全者应尽快手术,如IE累及二尖瓣、三尖瓣且无瓣膜结构的严重损毁者,施行瓣膜成形术是较好的方法。

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
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