west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "大数据" 55 results
  • Part Ⅸ of database building: tag and structure of the neoadjuvant therapy of colorectal cancer

    ObjectiveTo describe the constructive process of neoadjuvant therapy for colorectal cancer part in the West China Colorectal Cancer Database (DACCA).MethodWe used the form of text description.ResultsThe specific concept of neoadjuvant therapy for colorectal cancer including neoadjuvant treatment therapies, compliance of patients with neoadjuvant therapy, neoadjuvant therapy intensity scheme, the CEA value of patients during neoadjuvant therapy, changes of symptoms, changes of primary tumor size in colorectal cancer, and TRG grading of the DACCA in the West China Hospital were defined. Then the neoadjuvant therapies were detailed for their definition, label, structure, error correction, and update.ConclusionThrough detailed description and specification of neoadjuvant therapy for colorectal cancer in DACCA in West China Hospital, it can provide a reference for the standardized treatment of colorectal cancer and also provide experiences for the peers who wish to build a colorectal cancer database.

    Release date:2021-06-24 04:18 Export PDF Favorites Scan
  • Database-assisted study: geographical distribution of colorectal cancer in regional medical center—a report under real world data combined with Tableau map

    ObjectiveTo analyze the geographical distribution of patients with colorectal cancer by screening the current Database from Colorectal Cancer (DACCA) version in West China Hospital.MethodsThe selected DACCA database version of this data analysis was updated on September 5, 2019, and the two data of the " date of operation” and " address” were selected as the main research items. The characteristics of each selected data item were analyzed, and then the selected data were used as a joint feature analysis.ResultsAccording to the condition of selection by " address”, 7 096 valid data rows from the whole nation were obtained, 6 551 valid data rows from Sichuan province were obtained, and 2 954 valid data rows from Chengdu city were obtained. The geographic information provided by the DACCA database showed that, with the year changing, the provincial distribution area of patients was mainly the southwest region with middle-east of Sichuan province as center, mainly including the parts of Chongqing, Yunnan, and Guizhou; The distribution area of the municipal level in Sichuan province was mainly the east region with axis of the " Mianyang-Chengdu-Ya’an”, and Chengdu was the core; The regional distribution of patients in the Chengdu was mainly within the third ring load with Wuhou District, the Jinniu District, and the Qingyang District as the core area.ConclusionThegeographical information provided by DACCA database shows the geographical distribution characteristics of patients in the past 20 years, reflecting the basic characteristics and changes of the service area of West China Hospital, and can provide a basis for medical policy makers in screening, diagnosing and treating of colorectal cancer, and key management areas of following-up.

    Release date:2020-02-24 05:09 Export PDF Favorites Scan
  • 癫痫大数据:临床和研究考虑—来自国际抗癫痫联盟癫痫大数据工作组的报告

    癫痫是一种具有不同病因、表型和基因型特征的异质性疾病。因此,癫痫的临床和研究方面也是多种多样的,从流行病学到分子,其范围涵盖了临床试验和结果、基因和药物发现、影像学、脑电图、病理学、癫痫外科手术和数字技术等许多领域。当前,癫痫数据以 TB 和 PB 的形式收集,突破了其能力的极限。现代计算技术在机器和深度学习方面的优势和进步已经在其他疾病中开创了先河,也为癫痫领域开辟了令人兴奋的可能性。然而,若无精心设计的方法来获取、标准化、管理和提供此类数据,则存在着失败的风险。因此,通过利益相关者的密切投入,仔细构建相关的本体,为更雄心勃勃的大数据事业(如数据共享)提供了必要的支架。在本研究中,我们评估了大数据领域的癫痫临床和研究前景、当前挑战和未来方向,并提出了癫痫大数据的系统化处理方法。

    Release date:2021-04-25 09:50 Export PDF Favorites Scan
  • 在人类表型本体论中对癫痫发作进行建模—根据当代ILAE概念使大的表型数据易于处理

    癫痫的临床特征决定了如何定义癫痫,进而指导治疗。因此,在对癫痫病因、轨迹和治疗反应的研究中,考虑构成癫痫的基本临床实体至关重要。人类表型本体论(Human phenotype ontology,HPO)广泛应用于临床和遗传学研究中用于临床特征的简明交流和建模,其允许使用逻辑推理来协调提取的数据。我们试图重新设计HPO癫痫亚本体,以提高其与当前癫痫概念的一致性,同时支持在高通量临床和基因组研究中应用大型临床数据集。根据2017年国际抗癫痫联盟对癫痫发作类型的分类,我们创建了一个新的HPO癫痫亚本体,并在不同细节层次上整合了癫痫持续状态、热性惊厥、反射性发作和新生儿癫痫的概念。我们比较了修订前后的HPO癫痫亚本体,根据3个独立队列中791例患者的癫痫发作信息可以推断:其中2个独立队列的信息先前已发表过,还有150例患者是新招募的。每个队列的数据以不同的格式提供,并通过两个版本的HPO进行协调。新的癫痫亚本体将癫痫发作的描述性概念数量增加了5倍。可标注到队列中的癫痫发作描述符号数量增加了40%,关于个体癫痫发作的信息总量增加了38%。最重要的定性差异是局灶性进展为双侧强直-阵挛发作与全面起始和局灶起始发作的关系。我们已经生成了一个详细的当代概念图,用于协调临床癫痫发作数据,并在2020-12-07 HPO的官方版本中实施,并在hpo.jax.org免费提供。这将有助于克服基因组学中的表型瓶颈,促进有价值数据的再利用,并最终提高对癫痫的诊断和精准治疗。

    Release date:2022-10-31 09:25 Export PDF Favorites Scan
  • Part Ⅲ of database building: tag and structure of comorbidities and preoperative physical status of colorectal cancer

    ObjectiveTo explain surgical and medical comorbidities and preoperative physical status of colorectal cancer in detail as well as their tags and structures of Database from Colorectal Cancer (DACCA) in West China Hospital.MethodThe article was described in words.ResultsThe definition to the surgical comorbidities with its related content module, the medical comorbidity with its related content modules, and the preoperative physical status and characteristics of the DACCA in West China Hospital were given. The data label corresponding to each item in the database and the structured way needed for the big data application stage in detail were explained. And the error correction notes for all classification items were described.ConclusionsThrough the detailed description of the medical and surgical comorbidities and the preoperative physical status of DACCA in West China Hospital, it provides the standard and basis for the clinical application of DACCA in the future, and provides reference for other peers who wish to build a colorectal cancer database.

    Release date:2019-09-26 10:54 Export PDF Favorites Scan
  • Research on the application of personal digital assistant information system based on “VariFlight” in the operation management of third-grade class-A hospital

    Objective To explore the impact of personal digital assistant (PDA) information system on surgery operations, so as to provide basis for improving the efficiency of surgery operations and building medical research databases. Methods The data of patients undergoing surgical treatment in Northern Jiangsu People’s Hospital between October 1, 2018 and September 30, 2020 were retrospectively analysised. According to whether to operate the PDA information system, the patients who did not use the PDA information system for surgical treatment between October 1, 2018 and September 30, 2019 were taken as the control group (before the operation), and the patients who used the PDA information system for surgical treatment between October 1, 2019 and September 30, 2020 were taken as the intervention group (after the operation). The quality of surgical operation, the time of anesthesia opening, the time of opening operation, the length of operation, and other operation indicators before and after the operation of the PDA information system were analyzed. Results A total of 59 610 patients were enrolled, including 27 726 in the control group and 31 884 in the intervention group. Compared with before the operation of the PDA information system, the total annual operation increased by 4 158 cases (15.00%), and the average turnover of per operation room increased (17.10%). The average anesthesia opening time is 14.52 minutes earlier. The average operation opening time is 18.25 minutes earlier. Except for gastrointestinal center surgery, thoracic surgery, neurology surgery, trauma center surgery, intensive care unit ward surgery, biliary and pancreatic surgery, hepatosplenic surgery, and other types of surgery (P>0.05), other types of surgeries were statistically significant differences in the operation duration before and after other operations (P<0.05). Conclusions The PDA information system developed based on "VariFlight" quantifies the quality of surgical operations more finely. It can effectively improve the operation efficiency and economic benefits of surgery, shorten the operation time, contribute to the construction of medical research databases.

    Release date: Export PDF Favorites Scan
  • Research supercomputing platform construction and management practice of West China Biomedical Big Data Center of Sichuan University

    In the context of informatization and digitization, medical big data has become crucial for promoting medical research and technological innovation, posing unprecedented challenges to the construction and operation of big data research supercomputing platforms. This article systematically elaborates on the construction plan of the scientific research supercomputing platform of the West China Biomedical Big Data Center of Sichuan University, as well as the management and service models that support data research. It also compares the scale and operation of existing scientific research supercomputing platforms at home and abroad, providing a reference for the construction and management of medical big data scientific research supercomputing platforms in other institutions.

    Release date:2024-12-27 02:33 Export PDF Favorites Scan
  • Research progress on the application of “patient profile” based on big data in the field of nursing

    “Patient profile” is a specific application of user profile technology in the field of healthcare. As an emerging means of integrating health information, it provides personalized and precise health management for patients by analyzing multidimensional health data, improving health management effectiveness, reducing medical costs, and increasing their satisfaction and participation. It has broad application prospects in the field of nursing, but the current research status of its application in the field of nursing is not clear. This article reviews the application progress of patient profile based on big data in the field of nursing at home and abroad, systematically analyzes its construction methods, application scenarios, implementation effects and challenges, and puts forward relevant suggestions, aiming to provide references for the precise and intelligent development of nursing services.

    Release date:2025-08-26 09:30 Export PDF Favorites Scan
  • The application and challenge of artificial intelligence and big data in clinical engineering

    With the development of society and the progress of technology, artificial intelligence (AI) and big data technology have penetrated into all walks of life in social production and promoted social production and lifestyle greatly. In the medical field, the applications of AI, such as AI-assisted diagnosis and treatment, robots, medical imaging and so on, have greatly promoted the development and transformation of the entire medical industry. At present, with the support of national policy, market, and technology, we should seize the opportunity of AI development, so as to build the first-mover advantage of AI development. Of course, the development and challenges are coexisted. In the future development process, we should objectively analyze the gap between our country and developed countries, think about the unfavorable factors such as AI chips and data problems, and extend the application and service of AI and big data to all links of medical industry, integrate with clinic fully, so as to better promote the further development of AI medicine treatment in China.

    Release date:2019-06-25 09:50 Export PDF Favorites Scan
  • Preliminary analysis of epilepsy patients’ EEG big data based on CAAE new EEG reporting system

    ObjectiveTo discuss the scientific research and application value of the new China Association Against Epilepsy (CAAE) EEG reporting system, and to explore the model of establishing EEG database of tertiary comprehensive epilepsy center. MethodsA retrospective study was performed on outpatients who underwent EEG examination at the Epilepsy Center of Tsinghua University Yuquan Hospital from May 2021 to May 2022, and who also received EEG reports using the CAAE new EEG reporting system. We integrated the data of these 6380 patients with the previous database of our Epilepsy Center, and combined the two for the preliminary big data analysis. Results Among 6380 patients, normal EEG was reported in 2253 cases (35.3%) ,abnormal EEG in 4031 cases (63.2%), no definite abnormality in 96 cases. According to age groups, there were 3290 cases in children (51.0%), 1372 cases in adults (22.0%), 753 cases in adolescents (12.0%), 730 cases in infants (11.0%) and 235 cases in infants (4.0%).A total of 1466 (23.0%) patients were recorded with paroxysmal events, including 874 (60.0%) epileptic events. 517 (35.0%) non-epileptic events. ConclusionThe new EEG reporting system can provide a large number of researchable EEG data to guide clinical work, and it is an important tool for data sharing and big data research in the future.

    Release date:2023-01-04 02:32 Export PDF Favorites Scan
6 pages Previous 1 2 3 ... 6 Next

Format

Content