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find Author "刘雪梅" 32 results
  • History, Progress and Role of Systematic Review

    Release date:2016-08-25 02:48 Export PDF Favorites Scan
  • 用质量控制和技术规范改善胸心血管外科临床结果—2018 新春寄语

    Release date:2018-01-31 02:46 Export PDF Favorites Scan
  • 来氟米特治疗难治性肾病综合征

    目的 观察来氟米特治疗原发性难治性肾病综合征的疗效及安全性。 方法 2007年3月-2009年8月对传统免疫抑制剂治疗无效或反复发作的原发性难治性肾病综合征19例,应用来氟米特联合中等剂量糖皮质激素治疗。治疗前后每月测定24 h尿蛋白定量,血清白蛋白、血脂、血肌酐、尿素氮,血、尿常规,肝、肾功能等。观察期9个月。 结果 总有效率为73.7%,24 h尿蛋白定量从治疗前的(7.3±2.2)g/d,下降到(1.6±1.5)g/d(P<0.05),血清白蛋白有不同程度升高,从治疗前的(18.5±5.2) g/L升高到(34.4±4.2) g/L(P<0.05)。 结论 来氟米特联合糖皮质激素对原发性难治性肾病综合征有效,且短期不良反应少。

    Release date:2016-09-08 09:49 Export PDF Favorites Scan
  • 交互式教学在医学留学生见习课堂中应用

    目的探讨交互式教学模式在留学生临床见习中的应用及效果,为完善留学生临床见习课教学方法,提高临床见习带教质量提供参考。 方法选择2012年9月-2013年1月在四川大学见习的留学生77名,针对留学生临床见习和特殊性的学习特点及见习要求,尝试采用交互式教学模式,并采用座谈会及无记名问卷调查方法,在学生见习结束后就交互式教学模式效果的满意度进行统计分析。 结果77名留学生中共有64名完成有效问卷调查,其对小组病例讨论满意度最高,为87.1%;临床进展专题讲座和专人带教上满意度较低,仅为72.6%和62.4%,这两点尤为需要改善。 结论交互式教学模式有助于留学生临床见习效果的提高,但目前见习教师安排在一度程度上不利于留学生见习,有待改进及完善。

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  • Report Guidelines for Systematic Review and Meta-analysis: A Systematic Review

    Objective To collect the report guidelines for systematic reviews and meta-analyses, so as to provide support for the standardized publish and spread of those guidelines. Methods Such databases as Ovid MEDLINE (1996-2010) and EMbase (till April, 2010) were searched with the terms of “guideline”, “report”, “systematic review” and “meta-analysis” to collect the report guidelines for systematic reviews and meta-analyses. The irrelevant literatures (e.g. systematic review of a specific disease, clinical guideline for a certain disease, and other literatures focusing on the methodology of systematic review without mentioning reporting guideline) were excluded by reading the abstracts and titles, and then the further verification was done after the full-texts had been read. The contents about how to report a systematic review or meta-analyses were extracted from the included studies which were classified by its form of the original research (e.g. randomized controlled trial, observational study, diagnostic trial, etc.). Results Primary search ended up with 285 literatures, and 26 literatures of which were included. Among the included literatures about the report guidelines for systematic reviews and meta-analyses, eight were about RCTs, two about non-RCTs, two about observational study, no literature about diagnostic trial, one about animal experiment, two about report searching strategy, five about quality assessment, six about the influence on quality, and the other two about the update of guidelines. Conclusion The report guidelines for systematic reviews and meta-analyses are considerable in number, among which the QUOROM and its updated version PRISMA are relatively mature and widely applied. Report guidelines are beneficial to improve the quality of systematic reviews and meta-analyses, and the report guideline focusing on specific field is needs to be formulate.

    Release date:2016-09-07 11:06 Export PDF Favorites Scan
  • 促进《胸外科围手术期气道管理专家共识》的转化与更新——胸外科气道管理论坛亮点总结

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  • Patient Value and Preference in Evidence-Based Medicine

    Objective To undertake a preliminary study of the concept and approach of patient value and preference and to learn how to understand and elicit patient preference in the light of evidence-based medicine so as to promote evidence-based practice and improve the relationship between clinicians and patients. Methods The searching key words were developed and pertinent data were retrospectively retrieved for the years of 1992-2002. MEDLINE and CBMdisc were searched along with handsearching 9 Chinese medical journals and 4 evidence-based medicine books. Data were scanned and analyzed. Results A total of 2 646 related articles were identified, most of which were found in MEDLINE (2 403), followed by CBMdisc (185) and the journals (58). Currently there is no original article to study in this field from a point of view of evidence-based medicine in China. Conclusion Patient value and preference have been emphasized in the approach of evidence-based medicine and it is a worthwhile topic for us to explore.

    Release date:2016-09-07 02:27 Export PDF Favorites Scan
  • Glycyrrhizin for chronic hepatitis: protocol of systema tic review of randomized controlled trials

    Backgroud Chronic hepatitis is the major infectious disease of liver. There is no effective drug for it up to now. Clinical trials have showed that glycyrrhizin have potentional effective for chronic hepatitis. Objective To evaluate the effectiveness, safety and economics of glycyrrhizin for chronic hepatitis B and C. Search strategy The search terms include glycyrrhizin and its products’ name, chronic hepatitis and chronic carrier status. The thais registers of the Cochrane Hepato-Biliary Group, the Cochrane Complementary Medicine Field, and the central database of The Cochrane Library as well as MEDLINE, EMBASE and Chinese Biomedical CD Database were searched from their date of inception onward. And the free Internet search was operated to find ongoing and unpublished researches. Twenty Chinese medical journals and relevant academic conference proceedings have been searched by manual method. The reference lists of identified documents were checked as the complementary search. Inclusion criteria All randomized trials that tested glycryyhizin for chronic hepatitis B virus or hepatitis C virus infection were included in this review. Method of the review According to the principle of Cochrane systematic review, selection of thai for inclusion, assessment of methodological quality, data extraction and data syntheses were conducted by two reviewers.

    Release date:2016-08-25 03:17 Export PDF Favorites Scan
  • 利用系统评价证据提高医学研究的科学性和伦理性

    Release date:2016-08-30 05:57 Export PDF Favorites Scan
  • 多学科协作促进共识更新——中国胸外科气道管理协作组筹备会议亮点

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