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find Author "刘敏" 66 results
  • 先天性马蹄内翻足病因学研究

    Release date:2016-09-08 10:02 Export PDF Favorites Scan
  • 先天性尺桡骨融合的外科治疗进展

    先天性尺桡骨融合是一种较为罕见的先天性骨发育畸形,患肢前臂往往固定在旋前位,其功能受限程度取决于畸形的严重程度,以及是否为双侧受累。其外科治疗一直是小儿矫形外科所面临的难题。如何有效地改善患儿前臂的旋转功能,使前臂处于最佳的旋转功能,以提高患儿的日常生活能力,是治疗该病的中心环节,但其治疗效果不甚满意。现就其外科治疗进展进行综述。

    Release date:2016-09-08 09:18 Export PDF Favorites Scan
  • 老年科642例危急值报告分析

    目的 分析老年科常见危急值,讨论危急值报告的临床价值和意义。 方法 收集2010年10月-2011年10月642例危急值报告结果,分析危急值发生的时间、种类及原因。 结果 老年科危急值多发生在8︰00~18︰00时段,共484例 (75.39%),其血钾异常282例(43.93%)、肌钙蛋白增高261例(40.65%)为危急值主要表现。 结论 根据老年科危急值分布的时间特点和种类,合理安排人力资源,针对性地强化药品配置与管理,全面执行危急值报告制度是确保老年患者治疗安全的重要手段。

    Release date:2016-09-07 02:34 Export PDF Favorites Scan
  • 浅谈筹备申报药物临床试验机构资格认定的关键环节

    我国对开展药物临床试验的医疗机构实施准入制度。现对药物临床试验组织机构建设、药物临床试验质量管理规范(GCP)培训、材料组织3个环节的做法进行阐述,体现其在筹备申报药物临床试验机构资格认定工作中的关键作用。

    Release date:2016-09-07 02:33 Export PDF Favorites Scan
  • 伤口愈合和过度愈合的研究进展

    Release date:2016-09-01 11:37 Export PDF Favorites Scan
  • 降钙素原与创伤的研究进展

    创伤是导致炎症反应的重要因素之一,炎症反应和感染是创伤后常见的病理生理过程,而由此所致的脓毒症或脓毒症休克是创伤后患者死亡的重要原因。感染的早期诊治与预后密切相关。临床上许多感染监测指标如体温、C反应蛋白、白细胞计数、白细胞介素6和肿瘤坏死因子α等诊断感染缺乏特异性,而血培养阳性率低、耗时长且较难区分细菌定植或感染,在临床应用受到很大的限制,使得临床医师对于创伤后感染的诊断更加困难。近年来降钙素原(PCT)是被认为是诊断细菌感染有效的生物学指标。诸多研究认为PCT可以作为诊断创伤后并发症的工具,其水平的高低与创伤的严重程度及预后相关。现就PCT与创伤的研究进展进行综述。

    Release date:2016-09-08 09:14 Export PDF Favorites Scan
  • 硅胶内衬套治疗地震挤压伤截肢术后1例报告

    目的:观察硅胶内衬套应用于地震挤压伤截肢术后患者残端渗液不止的治疗效果。方法:采用个案分析。14岁女性少年,因地震挤压伤致左小腿中上段截肢,给予综合康复治疗,伤口愈合后安装假肢,残端出现水泡,原伤口少量浆液性液体渗出不止,给予加戴硅胶内衬套。结果:患者残端伤口渗液逐渐减少,水泡消失,正常熟练使用假肢,日常生活活动能力提高,正常上学。结论:硅胶内衬套是处理截肢术后残端渗液较好的方法。

    Release date:2016-09-08 09:54 Export PDF Favorites Scan
  • Forensic Pathologic Analysis of Traumatic Brain Injury

    【摘要】 目的 探讨颅脑损伤(BI)死亡的法医病理学特点,以及继发性脑干损伤、并发症的发生与死亡之间的因果关系。方法 从性别、年龄、致伤方式、损伤类型、生存时间、死亡原因等方面,对四川大学华西法医学鉴定中心1998年1月-2008年12月127例BI死亡尸检案例进行回顾性统计研究分析。结果 127例法医病理学检案中,原发性BI死亡51例(402%),继发性脑干损伤死亡61例(480%),并发症死亡15例(118%),其中伤后12 h内死亡者直接死因均为严重原发性脑损伤,存活12 h~1周者直接死因以继发性脑干损伤居多,生存时间超过1周者约半数死于并发症。结论 在BI案例的死亡原因确定时,应在全面系统的病理学检验基础上,结合案情及临床资料进行综合分析。【Abstract】 Objective To explore the characteristics of forensic pathology in traumatic brain injury and the relationships between secondary brainstem damage, complications and the causes of death. Methods 127 cases were reviewed from gender, age, manner of injury, survival time and the direct causes of death from January 1998 to December 2008. Results Of the 127 cases, the key direct cause of death was secondary brainstem damage, followed by severe primarily brain injury and complications. For those who died within 12 hours after injury, the direct cause was severe primarily brain injury; for those who survived between 12 hours to one week, secondary brainstem damage was in the majority of the causes and for those who survive more than one week time, complication was an important cause. Conclusion In the cases of traumatic brain injury, we should take comprehensive and systematic examination of forensic pathology, and refer to clinical data at the same time to determine the direct cause of death.

    Release date:2016-09-08 09:45 Export PDF Favorites Scan
  • 罕见胸内巨大恶性外周神经鞘膜瘤1例

    Release date:2016-09-08 09:56 Export PDF Favorites Scan
  • IMPACT OF SALTER INNOMINATE OSTEOTOMY ON ACETABULAR MORPHOLOGY AND DIRECTION IN DEVELOPMENTAL DISLOCATION OF THE HIP BY THREE-DIMENSIONAL COMPUTER TOMOGRAPHY

    ObjectiveTo investigate the impact of the Salter innominate osteotomy on the acetabular morphology and direction and the relationship between them in children with developmental dislocation of the hip (DDH) by three-dimensional CT. MethodsBetween January 2013 and January 2015, 51 patients with unilateral DDH were treated. All patients were females with an average age of 2 years and 5 months (range, one year and 6 months to 5 years). All the patients underwent open reduction of the hip, Salter innominate osteotomy, proximal femoral osteotomy, and hip cast immobilization for treatment. The data of three-dimensional CT before surgery and at 1 week after surgery were measured and collected as follows:the anterior acetabular index (AAI), posterior acetabular index (PAI), axial acetabular index (AxAI), acetabular anteversion angle (AAA) of the acetabulum, and the distances of the forward, outward, and lateral rotation of the distal osteotomy fragments. The differences of AAI, PAI, AxAI, AAA between before and after surgeries were compared and the difference values of the data with significant difference results were calculated. The relationship between the difference values and the distances of three different rotation directions before and after surgeries were tested by Spearman correlation analysis. ResultsThere were significant differences in the AAI, PAI, and AAA between before and after surgery (P<0.05), but no significant difference was found in the AxAI between before and after surgery (t=0.878, P=0.384). The difference values of AAI, PAI, and AAA were (4.518±4.601), (4.219±6.660), and (3.919±4.389)° respectively. The distances of the outward, lateral, and forward rotation of the distal osteotomy fragments after surgery were (0.420±0.339), (2.440±0.230), and (0.421±0.311) cm. There was a significant correlation between the three different rotation directions and AAI difference (P<0.05), especialy the outward rotation (r=0.981). There was a correlation between the outward, forward rotation and PAI, AAI differences (P<0.05), and no significant correlation between the lateral rotation and PAI, AAA was found (P>0.05). There was a significant correlation between the forward rotation and AAA difference (r=0.841). ConclusionSalter innominate osteotomy can increase the curvature of the anterior wall of the acetabulum in DDH, but reduce the curvature of the rear wall. At the same time, it can also change the direction of the acetabulum, significantly decrease the acetabular anteversion, but it can not change the depth of the acetabulum. The main factors of the curvature change after Salter innominate osteotomy of DDH is attributable to outward rotation, followed by forward rotation, and the main factor of the acetabular direction change is attributable to forward rotation.

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