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find Keyword "临床应用" 103 results
  • 单链抗体的原核可溶性表达及临床应用

    利用原核表达系统表达外源基因来获取大量有活性的蛋白质是目前最常用且经济的方法。由于原核表达系统的自身特点,单链抗体的表达往往以无活性的包涵体存在,研究者为解决此问题探索了许多方法。现就在大肠杆菌中表达可溶单链抗体的策略以及临床应用研究作一综述。

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  • THE APPLICATION OF SODIUM HYALURONATE IN JOINT DISEASES

    OBJECTIVE To review the physiological function of sodium hyaluronate in joints and its clinical applications. METHODS Many literatures were reviewed and analysed on therapeutic mechanism and the application foreground of sodium hyaluronate. RESULTS Extrinsic sodium hyaluronate plays an important role in improving synovial fluid and protecting cartilages as well as suppressing inflammation, so it is used in the treatment of joint diseases such as knee osteoarthritis, rheumatoid arthritis or temporomandibular osteoarthritis. CONCLUSION Sodium hyaluronate possesses a good applied prospect in joint diseases.

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  • CLINICAL APPLICATION OF PERCUTANEOUS LASER DISC DECOMPRESSION IN THE TREATMENT OF CERVICAL DISC HERNIATION

    Objective To evaluate the clinical effect of percutaneous laser disc decompression (PLDD) in the treatment of cervical disc herniation. Methods From March 2003 to December 2005, 47 patients with cervical disc herniation(96 cervical disc) were treated with PLDD. There were 25 males and 22 females with an average age of 56 years, ranging from 37 to72 years. The lesion were located at the levels of C3,4 in 20 discs, C4,5 in 27 discs, C5,6 in 31 discs, C6,7 in 18 discs. The laser fiber was introduced into the center of the herniated disc space by percutaneous puncture from anterior neck surface under fluoroscopic guidance. Laser reduced the intradisc pressure through the vaporization of disc nucleu. The adopted laser was semiconducted with a wavelength of 810 nm. Each laser output power was15 W with 1 s emission and 2 s interval. The total laser output power was decided depending on the degenerative degree of the disc and the reactive process of heat, ranging from 300 to 1 000 J.Results Of 47 patients,42 were followed up for 3 to 31 months (mean 13 months). The clinical evaluation was classified as excellent in 18 cases (42.9%), good in 14 cases (33.3%), fair in 6 cases (14.3%) and poor in 4 cases (9.5%). The general response rate was 90.5%. The excellent and good rate was 76.2%. No complications occurred. Conclusion PLDD can relieve the symptoms and signs of patients suffering from cervical disc herniation with less complication. The manipulation of PLDD is easy, safe and mini-invasive.

    Release date:2016-09-01 09:22 Export PDF Favorites Scan
  • Review and Prospect of Clinical Application of EuroSCORE

    European system for cardiac operative risk evaluation(EuroSCORE) is one of the widely used and influential cardiac surgery risk assessment system. It was originally used to predict the quantitative score of probability of death after cardiac surgery. After that, it has been developed to predict long-term mortality and survival rate, ICU residence time, treatment costs, main complications and so on. EuroSCORE Ⅱ is the latest version, which is more accurate in predicting mortality, long term survival rate than the old one. But there are also some limitations as predicting limited range of the end, underestimating the mortality of critically endangered patients, lacking adequate preoperative risk factors and so on. This review article focuses on the production, development and clinical application of EuroSCORE.

    Release date:2016-10-19 09:15 Export PDF Favorites Scan
  • 外周静脉置入中心静脉导管术在高原地区肿瘤患者中的应用观察

    目的 探讨外周静脉置入中心静脉导管(PICC)术在高原地区肿瘤患者中的临床应用,为西藏地区更好开展PICC技术提供依据。 方法 回顾性分析2010年8月-2012年4月113例肿瘤患者临床资料。 结果 穿刺成功111例,失败2例,成功率为98.2%。发生相关并发症14例,发生率12.4%,其中导管异位6例(5.3%),导管相关性感染3例(2.7%),栓塞2例(1.8%),机械性静脉炎2例(1.8%),导管部分脱出1例(0.8%)。 结论 PICC置管是一种置管成功率高,保留时间长,并发症较少、可靠有效的静脉治疗新途径,可在高原地区广泛推广应用。

    Release date:2016-08-26 02:09 Export PDF Favorites Scan
  • Progress in basic research and clinical application of median nerve electrical stimulation

    Median nerve electrical stimulation is a common peripheral nerve electrical stimulation treatment technology in clinic. With simple operation, it has been widely used in clinical to promote coma after craniocerebral trauma, relieve pain, improve cognition, Parkinson’s disease and so on. However, its mechanism has always been a hot topic and difficult part. At present, there are a large number of clinical efficacy studies and animal experiments of median nerve electrical stimulation at home and abroad. This article reviews the clinical application and animal experiments of median nerve electrical stimulation in recent years, and summarizes its mechanism, hoping to contribute to relevant clinical applications and research.

    Release date:2023-05-23 03:05 Export PDF Favorites Scan
  • 肺功能检查在基层医院中的应用价值

    目的:探讨肺功能检查在基层医院的临床应用价值。方法:对我院2005年3月至2008年5月共3216例做肺功能检查的患者临床资料进行分类整理,并对其结果进行分析。结果:呼吸系统疾病患者有409人(占总检查人数的12.7%),其中确诊慢性阻塞性肺疾病(COPD)有302例且均有FEV1.0/FVC%lt;80%或FEV1.0占预计值的百分比lt;80%,小气道功能障碍;拟行胸腹部等外科手术患者有2675人(占总检查人数的83%),其中肺功能良好者1738人(占65%),轻度受损535人(占20%),中度受损267人(占10%),重度受损135人(占5%)。肺功能受损患者术后并发症发病率明显增高;煤工尘肺伤残鉴定132人(占总检查人数的4.1%),肺功能正常者5人(占3.7%),轻度受损66人(占20%),中度受损31人(占24%),重度受损30人(占22.7%)。结论:肺功能检查对呼吸系统疾病尤其是COPD的诊断,对外科手术术前肺功能的评估以及术后肺部并发症预防和对尘肺伤残鉴定有较大的临床应用价值。

    Release date:2016-09-08 09:54 Export PDF Favorites Scan
  • Application and research progress of robotic-arm in total knee arthroplasty

    ObjectiveTo summarize the application and research progress of robotic-arm in total knee arthroplasty (TKA).MethodsRelevant literature at home and abroad was extensively reviewed to analyze the advantages and disadvantages of robotic-arm assisted TKA (RATKA).ResultsAccurate reconstruction of lower extremity alignment and rotation alignment, accurate osteotomy and implant prosthesis in TKA are very important to improve the effectiveness and prolong the life of the prosthesis. Traditional TKA deviations occur in key links such as osteotomy due to operator’s operation. RATKA solves the above problems to a certain extent and can assist accurate osteotomy and implant prosthesis, and protect the soft tissues around the knee joint. Patients’ satisfaction after RATKA is high, and the operator’s learning curve is shorter, which improves the efficiency of the operation. But it also has disadvantages such as prolonged operation time, increased complications and medical costs.ConclusionPreliminary clinical application studies have shown that RATKA has satisfactory effectiveness, but its definite advantages compared with traditional TKA need to be confirmed by a large number of randomized controlled trials and long-term follow-up.

    Release date:2021-07-29 05:02 Export PDF Favorites Scan
  • ABSTRACTSTHE CLINICAL APPLICATION OF FASCIA LATA TO SUBSTITUTE VEIN VALVE FORVARICOSITY OF LOWER EXTREMITY

    he fascia lata substitute valve operation was performed for curing the supperficial varieositycaused by the deep vein incompotence of the lower extremity basing on the study of the sources ofblood supply and the vascular distribution features of the fascia lata. The fascia lata subetitute vein valve operations were done on three males with the age rangingbetween 22 and 44 years old, and the rerelts were satisfactory 2 and 6 months after oporation.

    Release date:2016-09-01 11:18 Export PDF Favorites Scan
  • Application status of patient-reported outcome-based symptom management in lung cancer surgery

    The postoperative symptom burden in patients with lung cancer is severe and adversely impairs their quality of life. Symptom management is the cornerstone of medical care. Patient-reported outcome (PRO)-based symptom management is being increasingly recognized as the best "patient-centered care" model in clinical practice. However, the precise implementation of this model in patients undergoing lung cancer surgery is hindered by the lack of a lung cancer surgery-specific scale, implementation standards, clinical application parameters and high-quality researches. The use of a precise and simple PRO scale and an electronic PRO platform may greatly improve the feasibility of implementing this model. Currently, the application of PRO-based symptom management in lung cancer surgery is still being explored and needs to be improved in clinical research and practice.

    Release date:2020-10-30 03:08 Export PDF Favorites Scan
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