Objective To evaluate the feasibility and efficacy of emergency percutaneous coronary intervention( PCI) under mechanical ventilation for the treatment of patients with acute myocardial infarction complicated with acute pulmonary edema. Methods The clinical data of 15 patients admitted to the emergency ward for acute pulmonary edema caused by acute myocardial infarction from 2007 to 2009 were retrospectively analyzed. These patients received emergency PCI under mechanical ventilatory support.Parameters involved changes of symptoms, arterial blood gas, left ventricular ejection fraction( LVEF) , plasma concentrations of B-type natriuretic peptide( BNP) , and high sensitivity reactive protein( hs-CRP) . Results All patients showed significant improvements in dyspnea, artery blood gas parameters after PCI( P lt;0. 01) .LVEF increased significantly after PCI compared with before weaning [ ( 37. 36 ±0. 02) % vs ( 47. 41 ±0. 02) % , F =461. 47, P lt; 0. 05] . The concentrations of BNP and hs-CRP returned to lower level 4 weeks after PCI [ ( 99. 34 ±5. 15) fmol /mL vs ( 430. 50 ±96. 08) fmol /mL, ( 8. 35 ±2. 49) ng/mL vs ( 89. 50 ±9. 30) ng/mL, both P lt;0. 01] . Conclusion Emergency PCI under mechanical ventilatory support is a feasible and effective approach for patients with acute myocardial infarction complicated with acute pulmonary edema.
Citation：
FANG Kuaifa,LIUWenbing,RAO Zhirong,WANG Ningsheng,YANG Youxiang. Efficacy of Percutaneous Coronary Intervention Plus Mechanical Ventilation in the Treatment of Acute Myocardial Infarction Complicated with Pulmonary Edema. Chinese Journal of Respiratory and Critical Care Medicine, 2010, 9(3): 281-283. doi:
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| 1. |
陈方, 计乐群, 温宝园, 等. 主动脉球囊反搏对冠心病泵衰竭的治疗作用. 中国介入心脏病学杂志, 1998, 6: 64-65 .
|
| 2. |
Groenning BA, Nilsson JC, Sondergaard L, et al. Evaluation of impaired left ventricular ejection fraction and increased dimensions by muitipule neurohumoral plasma concentyations. Eur J Heart Fail,2001, 3 : 699-708.
|
| 3. |
Stanek B, Frey B, Hülsmann M, et al. Prognostic evaluation of neurohumoral plasma levels before and during beta-blocker therapv inadvanced left ventricular dvsfunction. J Am Coll Cardiol, 2001 , 38 :436-442.
|
| 4. |
Ridker PM, Hennekens CH, Roitman-Johnson B, et al. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet, 1998 ,351: 88 -92.
|
| 5. |
Asada J, Tsuji H, Iwasaka T, et al. Usefulness of plasm a brain natriuretic peptide levels in predicting dobutam ine-induced myocardial ischemia. Am J Cardiol, 2004, 93: 702 -704.
|
| 6. |
Hoffmeister HM, Ehlers R, Büttcher E, et al. Relationship between minox myocardial damage and inflammatoxy acute phase reaction in acute coronary syndromes. J Thromb Thrombolysis, 2003, 15 : 33-39.
|
| 7. |
朱蕾, 戎卫海, 钮善福, 等. 经面罩机械通气治疗急性肺水肿的疗效观察. 中国呼吸与危重监护杂志, 2002, 1: 217-220.
|
| 8. |
朱蕾, 钮善福, 主编. 机械通气. 上海: 上海科学技术出版社,2001, 334 -339.
|
- 1. 陈方, 计乐群, 温宝园, 等. 主动脉球囊反搏对冠心病泵衰竭的治疗作用. 中国介入心脏病学杂志, 1998, 6: 64-65 .
- 2. Groenning BA, Nilsson JC, Sondergaard L, et al. Evaluation of impaired left ventricular ejection fraction and increased dimensions by muitipule neurohumoral plasma concentyations. Eur J Heart Fail,2001, 3 : 699-708.
- 3. Stanek B, Frey B, Hülsmann M, et al. Prognostic evaluation of neurohumoral plasma levels before and during beta-blocker therapv inadvanced left ventricular dvsfunction. J Am Coll Cardiol, 2001 , 38 :436-442.
- 4. Ridker PM, Hennekens CH, Roitman-Johnson B, et al. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet, 1998 ,351: 88 -92.
- 5. Asada J, Tsuji H, Iwasaka T, et al. Usefulness of plasm a brain natriuretic peptide levels in predicting dobutam ine-induced myocardial ischemia. Am J Cardiol, 2004, 93: 702 -704.
- 6. Hoffmeister HM, Ehlers R, Büttcher E, et al. Relationship between minox myocardial damage and inflammatoxy acute phase reaction in acute coronary syndromes. J Thromb Thrombolysis, 2003, 15 : 33-39.
- 7. 朱蕾, 戎卫海, 钮善福, 等. 经面罩机械通气治疗急性肺水肿的疗效观察. 中国呼吸与危重监护杂志, 2002, 1: 217-220.
- 8. 朱蕾, 钮善福, 主编. 机械通气. 上海: 上海科学技术出版社,2001, 334 -339.
