Objective
To explore the diagnosis value of the low dose multi-slice spiral computed tomography (MSCT) imaging in pulmonary fungal infection in order to improve its diagnosis level.
Methods
CT manifestations of 106 cases of pulmonary fungal infection confirmed by operation, pathology, mycetes cultivation and follow-ups of clinical therapy were retrospectively analyzed. All cases underwent low dose MSCT examinations including CARE dose 4D and sinogram affirmed iterative reconstruction technology, and 6 cases underwent contrast-enhanced CT scanning.
Results
Among the basic MSCT findings of pulmonary fungal infection, they showed patch-nodular type in 54 cases, solid variant in 38 cases, and tumor type in 14 cases. In all cases, 91 cases displayed as mulifocality, 83 cases as polymorphism and 78 cases as polytropy. Among the 106 cases with comparative distinctive MSCT manifestations, bud of branch sign were showed in 39 cases, halo sign in 32 cases, wedge shape consolidation in 19 cases, ice needle sign in 15 cases, crescentic sign in 11 cases, air ring sign in 6 cases, and contra-halo sign in 4 cases. The nodules in the cavities were not enhanced in enhanced scan in 5 cases.
Conclusions
There are some distinctive MSCT findings in patients with pulmonary fungal infection. Pulmonary fungal infection can be diagnosed with typical MSCT findings in close combination with the clinical information.
Citation：
QiYueyong, GuTao, CaiYuanqing, WangShuang, ZhouYu, ZouLiguang. Low Dose MSCT Diagnosis of Pulmonary Fungal Infection. Chinese Journal of Respiratory and Critical Care Medicine, 2016, 15(2): 158-160. doi: 10.7507/1671-6205.2016037
Copy
Copyright © the editorial department of Chinese Journal of Respiratory and Critical Care Medicine of West China Medical Publisher. All rights reserved
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- 1. Miki N, Yasuhiro F, Masaki Y, et al.Epidemiology of invasive fungal infections after liver transplantation and the risk factors of late-onset invasive aspergillosis.J Infect Chemother, 2016, 22:84-89.
- 2. 冯春来, 施毅.肺曲霉球诊治进展.中国呼吸与危重监护杂志, 2014, 13:427-429.
- 3. Pratibha G.Pulmonary fungal infections.Curr Med Res Pract, 2015, 5:221-227.
- 4. Andreas C, Margaret CL, Andrew CY, et al.CT patterns of fungal pulmonary infections of the lung:Comparison of standard-dose and simulated low-dose CT.Eur J Radiol, 2012, 81:2860-2866.
- 5. Martinez DR, Ananda-Rajah MR, Suominen H, et al.Automatic detection of patients with invasive fungal disease from free-text computed tomography (CT) scans.J Biomed Inform, 2015, 53:251-260.
- 6. Taisa DG, Dante LE, Edson M.Pulmonary infections following bone marrow transplantation:High-resolution CT findings in 35 paediatric patients.European J Radiol, 2008, 66:117-121.
- 7. Gafter-Gvili A, Paul M, Bernstine H, et al. The role of 18F-FDG PET/CT for the diagnosis of infections in patients with hematological malignancies and persistent febrile neutropenia. Leuk Res, 2013, 37:1057-1062.
- 8. Vos FJ, Donnelly JP, Oyen WJ, et al. 18F-FDG PET /CT for diagnosing infectious complications in patients with severe neutropenia after intensive chemotherapy for haematological malignancy or stem cell transplantation. Eur J Nucl Med Mol Imaging, 2012, 39:120.
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