To compare the effects of continuous subglottic drainage (CSSD) and intermittent subglottic drainage (ISSD) in ventilated patients.
We searched Pubmed, EMbase, The Cochrane Library, Web of Knowledge, CBM, Wanfang Data, CNKI, and VIP databases for the randomized controlled trials (RCTs) on the effects of CSSD and ISSD in ventilated patients published before August 2016. RevMan 5.3 software was used for data consolidation.
A total of 18 studies, 2 022 cases of patients were included in this study. Meta-analysis results showed that CSSD and ISSD produce similar effects on the incidence of ventilator-associated pneumonia (VAP), time to VAP, duration of mechanical ventilation, the drainage volume, length of hospital stay and mortality. But ISSD showed lower positive rate of occult blood test than CSSD.
CSSD and ISSD seem to exert similar effects, but ISSD offers more benefits on tracheal mucous protection, which warrants promotion for clinical application.